Klompas M, 2000, USA | 16 papers pooling sensitivity of pulse deficit in 1586 patients | Meta-analysis | Sensitivity | 31% (95% CI 24% to 39%) | Most studies lacked control group |
Most retrospective analysis of signs in patients with known dissection |
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Bossone E et al, 2002, Italy | 513 patients with type A aortic dissection confirmed on imaging, surgery, or postmortem examination | Mix of prospective diagnostic trial and retrospective review of case notes | Sensitivity | 30% | |
Mortality | 24.7% no pulse deficit | |
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Mehta RH et al, 2002, International | 550 patients with type A dissection in an international registry | Retrospective analysis of registry | Sensitivity | 30.1% | Small study considering five countries |
Retrospective review of diagnosed patients |
| | | | | May include patients from Bossone et al paper. |