Diagnostic criteria for GBS
Sensory GBS1 | Typical GBS2* |
---|---|
*Excluding diagnosis: diagnosis of botulism, myasthenia, poliomyelitis or toxic neuropathy; abnormal porphyrin metabolism; recent diphteria; purely sensory symptoms, without weakness. †Features required for diagnosis. | |
Acute onset of symmetric sensory loss | Progressive weakness in both arms and legs† |
Peak deficit achieved within four weeks | Areflexia† |
Diminished or absent reflexes | Progression of symptoms over days to four weeks |
Normal motor strength | Relative symmetry of symptoms |
Electrodiagnostic evidence of demyelination in at least two nerves | Mild sensory symptoms or signs |
Monophasic course | Cranial nerve involvement |
No other known cause for neuropathy | Recovering two to four weeks after progression ceases |
No family history of neuropathy | Autonomic dysfunction |
Albuminocytological dissociation in CSF | Absence of fever at onset |
Albuminocytological dissociation in CSF | |
Typical electrodiagnostic features |