Table 1

 Comparison of clinical/pathological features of maduramicin toxicity in different species.2–6

Animal speciesClinical/pathological features
CalvesSudden cardiac death
SheepLeg muscle weakness, myonecrosis, cardiomyopathy, arrhythmias
Cattle, steerCardiac arrhythmias, heart failure, cardiomyopathy
ChickenWatery diarrhoea, macrocytic anaemia, leucopoenia, lymphopenia
HumansMuscle weakness, myonecrosis, acute renal failure, polyneuropathy