Table 1

 Diagnostic criteria for Brugada syndrome

(1) Appearance of a coved type ST segment elevation (gradually descending terminal portion) in more than one right precordial lead, in the presence or absence of a sodium channel blocker and one of the following clinical criteria:
    Documented ventricular fibrillation
    Self terminating polymorphic VT
    Family history of SCD (<45 years)
    Coved type ECGs in family members
    Electrophysiological inductibility
    Syncope or nocturnal agonal respiration
The appearance of the ECG features, without these clinical symptoms, is referred to as an idiopathic Brugada ECG pattern (not BS)
(2) Appearance of saddle back type ST segment elevation (terminal portion >1 mm) in more than one right precordial lead under baseline conditions with conversion to coved type following challenge with a sodium channel blocker. Drug induced ST segment elevation >2 mm should raise the possibility of BS when one or more of the aforementioned clinical criteria are present.
(3) Appearance of saddle back type ST segment elevation (terminal portion <1 mm) in more than one lead under baseline conditions with conversion to coved type following challenge with a sodium channel blocker.