Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy (%, with 95% confidence intervals) of the anion gap for predicting the presence of lactic acidosis at different anion gap thresholds
| Threshold | Sensitivity | Specificity | PPV | NPV | Accuracy |
|---|---|---|---|---|---|
| AG >6 | 93.2 (86.8–99.6) | 17.3 (12.6–22.1) | 20.5 (15.6–25.5) | 91.8 (84.2–99.5) | 31.7 (26.4–36.9) |
| AG >12 | 58.2 (45.1–71.2) | 81.0 (76.2–85.9) | 40.5 (29.7–51.3) | 89.7 (85.8–93.7) | 76.9 (72.2–81.6) |