Table 2 Best fit multivariable model based on history and physical and the best fit model incorporating laboratory findings
PredictorReference groupOdds ratios (95% CI)
SCS Thal2.66 (1.12 to 6.31)
SS2.31 (1.08 to 4.95)
Other/unknown9.17 (3.56 to 23.65)
Pain in chestNo pain in chest2.35 (1.55 to 3.57)
Pain similar to previousPain not similar to previous0.60 (0.40 to 0.91)
ChillsNo chills3.85 (1.69 to 8.79)
Temperature abnormalTemperature normal4.37 (2.06 to 9.25)
Temperature not done0.74 (0.25 to 2.21)
Pulse oximetry abnormalPulse oximetry normal4.72 (2.63 to 8.50)
Pulse oximetry not done1.62 (0.87 to 2.99)
SCS Thal2.97 (1.15 to 7.65)
SS1.95 (0.83 to 4.56)
Other/unknown8.09 (2.84 to 23.08)
Pain in chestNo pain in chest1.83 (1.13 to 2.97)
Pain similar to previousPain not similar to previous0.54 (0.34 to 0.85)
ChillsNo chills2.42 (0.95 to 6.13)
Temperature abnormalTemperature normal5.35 (2.29 to 12.49)
Temperature not done0.80 (0.23 to 2.70)
Pulse oximetry abnormalPulse oximetry normal3.56 (1.85 to 6.85)
Pulse oximetry not done1.87 (0.93 to 3.74)
Haemoglobin <10Haemoglobin ⩾102.88 (1.68 to 4.94)
Haemoglobin not measured0.36 (0.09 to 1.38)
Nitrite positiveNitrite negative4.11 (1.35 to 12.56)
Nitrite not assessed0.80 (0.49 to 1.31)
Chronic abnormalityNormal on CXR1.82 (1.01 to 3.27)
Acute abnormality5.75 (2.69 to 12.31)
Not done0.71 (0.35 to 1.42)
  • CXR, chest x ray; SC, sickle cell haemogoblin C disease; SS, homozygous sickle cell disease; S Thal, sickle cell beta thalassaemia disease.

  • CXR, chest x ray; SC, sickle cell haemogoblin C disease; SS, homozygous sickle cell disease; S Thal, sickle cell beta thalassaemia disease.