Table 5

Sensitivity, specificity and likelihood ratios for each variable

FeatureSensitivitySpecificityPositive likelihood ratioNegative likelihood ratio
Male sex86/132 (65.2%)635/1444 (44.0%)1.16 (1.02 to 1.33)0.792 (0.623 to 1.01)
Nature of chest pain
    Indigestion/burning16/129 (12.4%)1307/1426 (91.7%)1.49 (0.91 to 2.43)0.956 (0.894 to 1.02)
    Stabbing/sharp18/129 (14.0%)1133/1426 (79.5%)0.679 (0.437 to 1.06)1.08 (1.0 to 1.17)
    Aching/dull/heavy59/129 (45.7%)774/1426 (54.3%)1.0 (0.822 to 1.22)1.0 (0.847 to 1.18)
    Gripping/crushing25/129 (19.4%)1219/1426 (85.5%)1.33 (0.919 to 1.94)0.943 (0.864 to 1.03)
    Non-specific/other11/129 (8.5%)1271/1426 (89.1%)0.784 (0.437 to 1.41)1.03 (0.971 to 1.08)
Site of chest pain
    Central101/131 (77.7%)424/1431 (29.6%)1.10 (0.992 to 1.21)0.773 (0.559 to 1.07)
    Left chest18/131 (13.7%)1141/1431 (79.7%)0.678 (0.436 to 1.05)1.08 (1.01 to 1.16)
    Right chest1/131 (0.8%)1396/1431 (97.6%)0.312 (0.043 to 2.26)1.02 (1.0 to 1.04)
    Other11/131 (8.4%)1332/1431 (93.1%)1.21 (0.668 to 2.20)0.984 (0.933 to 1.04)
Radiation of chest pain
    None43/130 (33.1%)842/1404 (60.0%)0.826 (0.642 to 1.06)1.12 (0.982 to 1.27)
    Left arm45/130 (34.6%)993/1404 (70.7%)1.18 (0.921 to 1.52)0.924 (0.812 to 1.05)
    Right arm9/130 (6.9%)1374/1404 (97.9%)3.24 (1.57 to 6.68)0.951 (0.907 to 0.997)
    Neck5/130 (3.8%)1331/1404 (94.8%)0.740 (0.304 to 1.80)1.01 (0.978 to 1.05)
    Jaw3/130 (2.3%)1347/1404 (95.9%)0.568 (0.181 to 1.79)1.02 (0.990 to 1.05)
    Back11/130 (8.5%)1241/1404 (88.4%)0.729 (0.407 to 1.31)1.04 (0.980 to 1.09)
    Other14/130 (10.8%)1296/1404 (92.3%)1.40 (0.827 to 2.37)0.967 (0.909 to 1.03)
Time of onset
    00:00–05:5926/121 (21.5%)1060/1288 (82.3%)1.21 (0.847 to 1.74)0.954 (0.866 to 1.05)
    06:00–11:5950/121 (41.3%)663/1288 (51.5%)0.852 (0.684 to 1.06)1.14 (0.973 to 1.34)
    12:00–17:5924/121 (19.8%)1048/1288 (81.4%)1.06 (0.731 to 1.55)0.985 (0.898 to 1.08)
    18:00–23:5921/121 (17.4%)1129/1288 (87.7%)1.41 (0.928 to 2.13)0.943 (0.867 to 1.03)
    Continuous74/111 (66.7%)393/1192 (33.0%)0.995 (0.867 to 1.14)1.01 (0.768 to 1.33)
Nausea43/127 (33.9%)948/1394 (68.0%)1.06 (0.820 to 1.36)0.973 (0.854 to 1.11)
Vomiting9/125 (7.2%)1293/1376 (94.0%)1.19 (0.615 to 2.32)0.988 (0.939 to 1.04)
Sweating59/128 (46.1%)808/1393 (58.0%)1.10 (0.909 to 1.34)0.929 (0.787 to 1.10)
Dyspnoea49/126 (38.9%)822/1381 (59.5%)0.961 (0.765 to 1.21)1.03 (0.887 to 1.19)
Previous coronary heart disease16/127 (12.6%)1227/1407 (87.2%)0.985 (0.611 to 1.59)1.0 (0.935 to 1.07)
Diabetes7/128 (5.5%)1309/1396 (93.8%)0.878 (0.415 to 1.85)1.01 (0.965 to 1.05)
Hypertension52/129 (40.3%)975/1382 (70.5%)1.37 (1.09 to 1.71)0.846 (0.731 to 0.979)
Hyperlipidaemia37/118 (31.4%)937/1300 (72.1%)1.12 (0.848 to 1.49)0.952 (0.839 to 1.08)
Smoker36/126 (28.6%)944/1386 (68.1%)0.896 (0.673 to 1.19)1.05 (0.934 to 1.79)
Ex-smoker26/123 (21.1%)1145/1326 (86.3%)1.55 (1.07 to 2.24)0.913 (0.831 to 1.0)
Cocaine use0/122 (0%)1300/1323 (98.3%)
Family history48/119 (40.3%)706/1303 (54.2%)0.880 (0.702 to 1.10)1.10 (0.942 to 1.29)
Chest wall4/108 (3.7%)1181/1259 (93.8%)0.598 (0.223 to 1.60)1.03 (0.987 to 1.07)
  • Differences in denominators for sensitivity and specificity are due to missing data.