Vital sign parameters classified as clinically significant
| Vital sign | Lower limit | Upper limit |
| Systolic blood pressure (mm Hg) | <90 (hypotension) | >180 (hypertension) |
| Pulse rate (per min) | <60 (bradycardia) | >100 (tachycardia) |
| Respiration rate (per min) | <8 (bradypnoea) | >24 (tachypnoea) |