Table 3

Sensitivity and specificity of combinations of biomarkers with troponin versus troponin alone

StudyCombinationTroponin aloneCombination
Sensitivity (95% CI)Specificity (95% CI)Sensitivity (95% CI)Specificity (95% CI)
Body 201112 TnI or H-FABP0.42 (0.33 to 0.51)0.96 (0.94 to 0.97)0.82 (0.74 to 0.88)0.88 (0.83 to 0.88)
Haltern 201018 TnT or H-FABP0.74 (0.66 to 0.74)1.0 (0.96 to 1.0)0.97 (0.86 to 0.99)0.65 (0.6 to 0.66)
McCann 200825 TnT or H-FABP0.75 (0.69 to 0.81)0.94 (0.9 to 0.96)0.93 (0.89 to 0.96)0.93 (0.89 to 0.96)
Mion 200726 TnI or H-FABP0.55 (0.39 to 0.7)0.98 (0.92 to 1.0)0.76 (0.6 to 0.87)0.93 (0.86 to 0.97)
  • Tn I, troponin I; H-FABP, heart-type fatty acid-binding protein.