Methoxyflurane (N=149) | Placebo (N=149) | Estimated treatment effect (95% CI) | p Value | |
---|---|---|---|---|
Adjusted* change from baseline (mm) | ||||
Overall | −30.2 | −15.2 | −15.1 (−19.2 to −11.0) | <0.0001 |
5 min | −23.1 | −11.3 | −11.8 (−15.6 to −8.0) | |
10 min | −28.9 | −14.8 | −14.1 (−18.4 to −9.8) | |
15 min | −34.0 | −15.5 | −18.5 (−23.4 to −13.5) | |
20 min | −35.0 | −19.0 | −16 (−21.3 to −10.7) | |
Time by treatment interaction | 0.0019 |
Pain scores recorded after the start of the planned emergency department procedure were excluded from the analysis. Pain scores taken after initiation of rescue medication were included in the analysis.
*Least squares mean has been adjusted for baseline pain score and age group (adolescent/adult).
N, number of patients.