Prevalence of definite SBI, possible SBI and IBI, and +LR for IBI related to the risk classification of the ‘step by step’ approach
| Risk classification of patients according to step by step approach | Definite SBI | Possible SBI | IBI | ||||
|---|---|---|---|---|---|---|---|
| n | (95% CI) | n | (95% CI) | N | % (95% CI) | +LR for IBI (95% CI) | |
| High risk before biomarkers (n=485) | 245 | 50.5 (46.0 to 54.9) | 20 | 4.1 (2.3 to 5.8) | 42 | 8.6% (6.1% to 11.1%) | 2.05 (1.89 to 2.22) |
| High risk after biomarkers (n=54) | 4 | 7.4 (0.4 to 14.3) | 12 | 22.2 (11.1 to 33.3) | 3 | 5.6% (0% to 11.6%) | 7.91 (4.24 to 14.75) |
| Intermediate risk (n=96) | 2 | 2.0 (0 to 4.9) | 13 | 13.5 (6.6 to 20.3) | 2 | 2% (0% to 4.8%) | 4.12 (1.81 to 9.37) |
| Low risk (n=488) | 1 | 0.2 (0 to 0.6) | 46 | 9.4 (6.8 to 12.0) | 1 | 0.2% (0% to 0.6%) | 1 |
IBI, invasive bacterial infection; LR; likelihood ratio; SBI, serious bacterial infection.