Comparison of THERM and NEWS (n=234)
| THERM | NEWS | |
|---|---|---|
| AUROC | 0.84 (0.79 to 0.88)* | 0.71 (0.64 to 0.76) |
| High risk cut-off | ||
| Sensitivity | 0.57 (0.40 to 0.73) | 0.65 (0.48 to 0.80) |
| Specificity | 0.89 (0.84 to 0.93)* | 0.71 (0.64 to 0.77) |
| LR+ | 5.32 | 2.2 |
| LR− | 0.48 | 0.5 |
| PPV | 0.50 (0.34 to 0.66) | 0.29 (0.20 to 0.40) |
| NPV | 0.92 (0.87 to 0.95) | 0.91 (0.86 to 0.95) |
| Medium risk cut-off | ||
| Sensitivity | 0.89 (0.75 to 0.97) | 0.92 (0.78 to 0.98) |
| Specificity | 0.65 (0.58 to 0.72)* | 0.44 (0.37 to 0.51) |
| LR+ | 2.55 | 1.65 |
| LR− | 0.17 | 0.18 |
| PPV | 0.32 (0.23 to 0.42) | 0.24 (0.17 to 0.31) |
| NPV | 0.97 (0.92 to 0.99) | 0.97 (0.91 to 0.99) |
All figures are given as fractions (95% CIs).
*Significant difference.
AUROC, area under the receiver operating characteristic curve; NEWS, National Early Warning Score; LR, likelihood ratio; PPV, positive predictive value; NPV, negative predictive value; THERM, The Resuscitation Management score.