Table 1

Comparison of mean monthly drug use density values expressed as DDD or RDD per 100 patient days in the medical emergency department preintervention and postintervention (before/after analysis using t test)

DDD/100RDD/100
Drug classPre-Post-Per cent changep ValuePre-Post-Per cent changep Value
Cephalosporins4131−24<0.013922−42<0.001
 3° Cephalosporins3411−68<0.0013411−68<0.001
 1°/2° Cephalosporins720214<0.001411202<0.001
Penicillins193999<0.001182222<0.01
 Piperacillin±BLI1411−22<0.0011612−22<0.001
 Aminopenicillins+BLI222835<0.00118782<0.001
 Narrow-spectrum penicillins36740.1112630.11
Carbapenems63−47<0.00142−49<0.001
Fluoroquinolones2117−22<0.051914−26<0.05
Aminoglycosides0.50.3−310.340.40.2−310.34
Glycopeptides21−67<0.00121−67<0.001
Macrolides/Clindamycin4032−20<0.052219−120.22
Total138128−70.2411186−23<0.001
  • BLI, bealactamase inhibitor; DDD, defined daily doses; RDD, recommended daily doses.