Sensitivity and specificity of combinations of biomarkers with troponin versus troponin alone
| Study | Combination | Troponin alone | Combination | ||
| Sensitivity (95% CI) | Specificity (95% CI) | Sensitivity (95% CI) | Specificity (95% CI) | ||
| Body 201112 | TnI or H-FABP | 0.42 (0.33 to 0.51) | 0.96 (0.94 to 0.97) | 0.82 (0.74 to 0.88) | 0.88 (0.83 to 0.88) |
| Haltern 201018 | TnT or H-FABP | 0.74 (0.66 to 0.74) | 1.0 (0.96 to 1.0) | 0.97 (0.86 to 0.99) | 0.65 (0.6 to 0.66) |
| McCann 200825 | TnT or H-FABP | 0.75 (0.69 to 0.81) | 0.94 (0.9 to 0.96) | 0.93 (0.89 to 0.96) | 0.93 (0.89 to 0.96) |
| Mion 200726 | TnI or H-FABP | 0.55 (0.39 to 0.7) | 0.98 (0.92 to 1.0) | 0.76 (0.6 to 0.87) | 0.93 (0.86 to 0.97) |
Tn I, troponin I; H-FABP, heart-type fatty acid-binding protein.