Characteristic of patients
| Total (N=763) | ADP positive* (N=446) | ADP negative† (N=317) | Missing values | p Value | |
|---|---|---|---|---|---|
| Demographics | |||||
| Age (years) | 58.2±14.0 | 63.5±13.1 | 50.7±11.6 | 0 (0) | <0.0001 |
| Male | 478 (62.2) | 315 (71) | 160 (50.3) | 0 (0) | <0.0001 |
| Risk factors | |||||
| Diabetes | 127 (16.7) | 94 (21) | 33 (10) | 3 (0.4) | <0.05 |
| Smokers‡ | 229 (30.0) | 118 (26.5) | 111 (34.9) | 2 (0.3) | <0.05 |
| Hypertension | 289 (37.8) | 208 (46.7) | 81 (25.5) | 6 (0.8) | <0.0001 |
| Dyslipidemia | 289 (30.0) | 118 (26.5) | 111 (34.9) | 2 (0.3) | <0.05 |
| Past MI | 183 (24) | 143 (45.0) | 40 (25.5) | 8 (10.5) | <0.0001 |
| Family history of coronary artery disease | 250 (32.8) | 154 (34.6) | 96 (30.1) | 57 (7.5) | 0.2 |
| Examinations and investigations | |||||
| Pain radiates to arms | 379 (49.7) | 249 (55.7) | 131 (40.2) | 4 (0.5) | <0.0001 |
| Pain worse on inspiration | 252 (33.0) | 120 (27.0) | 132 (41.5) | 108 (14.2) | <0.0001 |
| Chest pressure reproduces pain | 126 (16.5) | 38 (8.5) | 88 (27.7) | 14 (1.8) | <0.0001 |
| Diaphoresis | 375 (49.1) | 248 (55.7) | 127 (39.9) | 10 (1.3) | <0.0001 |
| Abnormal ECG | 211 (27.7) | 211 (46.5) | 0 (0) | 0 (0) | <0.0001 |
| Elevated troponin within 2 hours | 120 (15.7) | 120 (26.5) | 0 (0) | 0 (0) | <0.0001 |
| Overall MACEs | 79 (10.4) | 79 (17.4) | 0 (0) | 0 (0) | <0.0001 |
Values are mean±SD, n (%) or median (IQR). *EDACS >16, abnormal ECG or abnormal troponin within 2 hours. †EDACS ≤16, normal ECG and normal troponins at 2 hours. ‡Patient self-reported as a current smoker.
ADP, accelerated diagnostic pathway; EDACS, emergency department assessment of chest pain score; MACE, major adverse cardiac event; MI, myocardial infarction.