Median suPAR level (ng/mL) stratified according to demographics, disease severity and outcomes
| Variable | n (%) | Median | IQR | p Value |
|---|---|---|---|---|
| All | 4343 (100) | 3.2 | 2.3–4.7 | |
| Sex | ||||
| Male | 2075 (47.8) | 3.1 | 2.2–4.7 | |
| Female | 2268 (52.2) | 3.2 | 2.3–4.7 | 0.006 |
| Age (years) | ||||
| <50 | 1339 (30.8) | 2.3 | 1.8–3.0 | |
| 50–70 | 1313 (30.2) | 3.0 | 2.3–4.2 | |
| >70 | 1691 (38.9) | 4.4 | 3.2–6.1 | <0.0001 |
| Admission time | ||||
| 0 days | 2218 (51.1) | 2.6 | 1.9–3.6 | |
| 1 day | 565 (13.0) | 3.2 | 2.3–4.5 | |
| 2–4 days | 596 (13.7) | 3.7 | 2.7–5.3 | |
| 5–7 days | 371 (8.5) | 4.4 | 3.3–6.5 | |
| 8–9 days | 131 (3.0) | 5.0 | 3.4–7.3 | |
| 10 days or more | 462 (10.6) | 5.1 | 3.6–7.5 | <0.0001 |
| Admitted to ICU | ||||
| No | 4255 (98.0) | 3.2 | 2.2–4.6 | |
| Yes | 88 (2.0) | 5.6 | 3.0–7.9 | <0.0001 |
| Charlson score* | ||||
| 0 | 3177 (73.2) | 2.9 | 2.1–4.2 | |
| 1 | 827 (19.0) | 3.7 | 2.7–5.4 | |
| 2 | 227 (5.2) | 5.0 | 3.8–7.2 | |
| 3 | 65 (1.5) | 6.1 | 4.6–8.6 | |
| 4+ | 47 (1.1) | 7.2 | 4.8–10.9 | <0.0001 |
| Readmitted within 30 days | ||||
| No, alive | 3370 (77.6) | 3.0 | 2.2–4.2 | |
| No, dead | 191 (4.4) | 6.9 | 4.8–9.8 | |
| 1 readmission | 619 (14.3) | 3.8 | 2.7–5.5 | |
| 2+ readmissions | 163 (3.8) | 4.1 | 2.9–6.0 | <0.0001 |
| Readmitted within 90 days | ||||
| No, alive | 2893 (66.6) | 2.9 | 2.1–4.1 | |
| No, dead | 237 (5.5) | 6.8 | 4.8–9.5 | |
| 1 readmission | 741 (17.1) | 3.5 | 2.6–5.1 | |
| 2+ readmissions | 472 (10.9) | 4.0 | 2.8–5.7 | <0.0001 |
| Died within 30 days | ||||
| No | 4119 (94.8) | 3.1 | 2.2–4.5 | |
| Yes | 224 (5.2) | 6.8 | 4.7–9.9 | <0.0001 |
| Died within 90 days | ||||
| No | 3957 (91.1) | 3.0 | 2.2–4.3 | |
| Yes | 386 (8.9) | 6.4 | 4.5–9.1 | <0.0001 |
*Patients with a Charlson score of 4 or higher were pooled into one group.
ICU, intensive care unit; suPAR, soluble urokinase plasminogen activator receptor.