The sensitivity and specificity of the various T-MACS thresholds for ACS (derivation set)
Threshold for a positive test | Sensitivity (95% CI) | Specificity (95% CI) | Accuracy (95% CI) |
Low risk (ie, very low risk=negative test) | 98.7% (95.3% to 99.8%) | 47.6% (43.4% to 51.9%) | 58.6 (55.0 to 62.3) |
Moderate risk (ie, very low risk and low risk=negative test) | 94.0% (89.0% to 97.2%) | 68.5%(64.4% to 72.3%) | 74.0 (70.7 to 77.2) |
High risk (ie, very low risk, low risk and moderate risk=negative test) | 47.0% (38.9% to 55.3%) | 100.0% (99.3% to 100.0%) | 88.6 (86.3 to 91.0) |
Sensitivity is the proportion of true positives that are correctly identified by the test.
Specificity is the proportion of true negatives that are correctly identified by the test.
Accuracy is the proportion of correct decisions (ie, true positive+true negative) over the number of total tested.
ACS, acute coronary syndromes; T-MACS, Troponin-only Manchester Acute Coronary Syndromes.