Table 1

The sensitivity and specificity of the various T-MACS thresholds for ACS (derivation set)

Threshold for a positive testSensitivity
(95% CI)
Specificity
(95% CI)
Accuracy
(95% CI)
Low risk (ie, very low risk=negative test)98.7% (95.3% to 99.8%)47.6% (43.4% to 51.9%)58.6 (55.0 to 62.3)
Moderate risk (ie, very low risk and low risk=negative test)94.0% (89.0% to 97.2%)68.5%(64.4% to 72.3%)74.0 (70.7 to 77.2)
High risk (ie, very low risk, low risk and moderate risk=negative test)47.0% (38.9% to 55.3%)100.0% (99.3% to 100.0%)88.6 (86.3 to 91.0)
  • Sensitivity is the proportion of true positives that are correctly identified by the test.

  • Specificity is the proportion of true negatives that are correctly identified by the test.

  • Accuracy is the proportion of correct decisions (ie, true positive+true negative) over the number of total tested.

  • ACS,¬†acute coronary syndromes; T-MACS, Troponin-only Manchester Acute Coronary Syndromes.