Table 1

Admission rate and composite estimate of short-term (7–30 days) outcomes of patients presenting in ED with TLOC2

Author/year/countryPatients with
TLOC
Number admitted7–30 days death7–30 days non-fatal severe outcome*7–30 days non-fatal severe outcome* identified in the ED7–30 days non-fatal severe outcome* identified after initial visit
Costantino et al, 2008, Italy10 676218 (32%)5 (0.7%)36
(5.3%)
n/an/a
Brignole et al, 2006, Italy48 465178 (38%)6 (1.3%)n/an/an/a
Reed et al, 2010, UK25 1100541 (49%)17 (1.5%)79
(7.2%)
n/an/a
Ungar et al, 2015, Italy26 29592 (31%)1 (0.3%)n/an/a21
(7.1%)
Birnbaum et al, 2008, USA27 713613 (86%)4 (0.6%)57
(8.0%)
32
(4.5%)
25
(3.5%)
Grossman et al, 2007, USA28 293201 (69%)7 (2.4%)68
(23%)
56
(19%)
12
(4.1%)
Quinn et al, 2004, USA29 684376 (55%)5 (0.7%)79 (11.5%)n/an/a
Quinn et al, 2006, USA 15760448 (59%)3 (0.4%)108 (14.2%)54
(7.1%)
54
(7.1%)
Schladenhaufen et al, 2008, USA30 517312 (60%)5
(1.0%)
98
(19%)
80 (15.5%)18
(3.4%)
Sun et al, 2007, USA31 477277 (58%)n/a56 (11.7%)40 (8.6%)16
(3.4%)
Daccarett et al, 2011, USA32 254118 (46%)1
(0.4%)
15
(5.9%)
8
(3.1%)
7
(2.8%)
Thiruganasambandamoorthy et al, 2014, Canada33 50562 (12%)5
(1.0%)
49
(9.7%)
22
(4.4%)
27
(5.3%)
Thiruganasambandamoorthy et al, 2015, Canada34 3662†474 (13%)31 (0.9%)345 (10.3%)225 (6.7%)120 (3.6%)
Median  (IQR) 49 (32–59) 0.8
(0.6– 1.1)
10.3 (7.6– 13.0) 6.9 (4.5– 10.3) 3.6 (3.4– 5.3)
  • Reproduced by permission of Oxford University Press on behalf of the European Society of Cardiology.

  • *Non-fatal severe outcomes generally are defined as a significant new diagnosis, a clinical deterioration, serious injury with recurrence or a significant therapeutic intervention.

  • †3365 patients had 30-day follow-up.

  • TLOC, transient loss of consciousness.