SI | n* | Patients admitted, n | Positive LR (95% CI) | Sensitivity % (95% CI) | Specificity % (95% CI) | Misclassification (n) | Misclassification (%) |
SI<0.3 | 2 678 873 | 803 789 | 2.30 (2.29 to 2.30) | 1 (0.01 to 0.01) | 99 (0.99 to 0.99) | 83 723 441 | 15.90 |
SI<0.4 | 23 001 832 | 5 413 693 | 1.65 (1.65 to 1.65) | 7 (0.07 to 0.07) | 96 (0.96 to 0.96) | 94 826 592 | 18.01 |
SI<0.5 | 89 731 143 | 17 078 233 | 1.26 (1.26 to 1.26) | 21 (0.21 to 0.21) | 84 (0.84 to 0.84) | 138 226 823 | 26.26 |
0.5≤SI≤0.7 | 254 116 753 | 220 439 748 | 1.21 (1.21 to 1.21) | 49 (0.49 to 0.49) | 59 (0.59 to 0.59) | 257 040 362 | 48.82 |
SI>0.7 | 182 607 355 | 31 896 908 | 1.13 (1.13 to 1.14) | 39 (0.38 to 0.38) | 66 (0.66 to 0.66) | 201 465 685 | 38.27 |
SI>0.8 | 89 850 521 | 19 204 417 | 1.46 (1.45 to 1.46) | 23 (0.23 to 0.23) | 84 (0.84 to 0.84) | 134 093 833 | 25.47 |
SI>0.9 | 41 834 287 | 11 153 882 | 1.95 (1.95 to 1.95) | 13 (0.13 to 0.14) | 93 (0.93 to 0.93) | 102 178 669 | 19.41 |
SI>1.0 | 18 269 347 | 6 321 940 | 2.84 (2.83 to 2.84) | 8 (0.07 to 0.07) | 97 (0.97 to 0.97) | 88 277 613 | 16.78 |
SI>1.1 | 9 201 475 | 3 879 858 | 3.91 (3.90 to 3.91) | 5 (0.05 to 0.05) | 99 (0.98 to 0.98) | 84 093 905 | 15.97 |
SI>1.2 | 4 889 509 | 2 443 122 | 5.36 (5.35 to 5.37) | 3 (0.03 to 0.03) | 99 (0.99 to 0.99) | 82 655 411 | 15.70 |
SI>1.3 | 2 783 835 | 1 539 198 | 6.64 (6.62 to 6.65) | 2 (0.02 to 0.02) | 99 (0.99 to 0.99) | 82 357 585 | 15.64 |
SI>1.4 | 1 680 715 | 931 290 | 6.67 (6.65 to 6.69) | 1 (0.01 to 0.01) | 99 (0.99 to 0.99) | 82 470 281 | 15.67 |
SI>1.5 | 1 072 815 | 589 067 | 6.54 (6.51 to 6.56) | 1 (0.01 to 0.01) | 99 (0.99 to 0.99) | 82 546 827 | 15.68 |
SI>1.6 | 686 703 | 378 902 | 6.61 (6.57 to 6.64) | 0 (0.00 to 0.00) | 99 (0.99 to 0.99) | 82 581 045 | 15.69 |
SI>1.7 | 229 264 | 489 867 | 4.72 (4.69 to 4.75) | 0 (0.00 to 0.00) | 99 (0.99 to 0.99) | 82 683 485 | 15.71 |
SI>1.8 | 163 329 | 374 448 | 4.15 (4.13 to 4.18) | 0 (0.00 to 0.00) | 99 (0.99 to 0.99) | 82 699 936 | 15.71 |
*n denotes the number of patient encounters included in the study in each specific SI category.
LR, likelihood ratio; SI, shock index.