SI | n* | Patients who died, n | Positive LR (95% CI) | Sensitivity % (95% CI) | Specificity % (95% CI) | Misclassification (n) | Misclassification (%) |
SI<0.4 | 4 853 264 | 110 556 | 0.86 (0.85 to 0.86) | 1 (0.01 to 0.01) | 99 (0.99 to 0.99) | 6 559 387 | 8.96 |
SI<0.5 | 15 306 015 | 271 975 | 0.67 (0.66 to 0.67) | 6 (0.06 to 0.06) | 93 (0.93 to 0.93) | 16 689 300 | 22.79 |
0.5≤SI≤0.7 | 29 760 757 | 29 235 529 | 1.50 (1.50 to 1.50) | 14 (0.14 to 0.14) | 79 (0.79 to 0.79) | 42 607 648 | 58.17 |
SI>0.7 | 28 178 412 | 1 130 032 | 1.54 (1.54 to 1.55) | 41 (0.41 to 0.41) | 73 (0.73 to 0.73) | 27 845 583 | 38.01 |
SI>0.8 | 17 043 605 | 857 484 | 1.96 (1.95 to 1.96) | 59 (0.59 to 0.59) | 62 (0.62 to 0.62) | 17 255 872 | 23.56 |
SI>0.9 | 9 977 972 | 654 531 | 2.59 (2.59 to 2.60) | 44 (0.44 to 0.45) | 77 (0.77 to 0.77) | 10 596 145 | 14.47 |
SI>1.0 | 5 751 553 | 444 563 | 3.10 (3.09 to 3.10) | 34 (0.34 to 0.34) | 87 (0.87 to 0.87) | 6 789 662 | 9.27 |
SI>1.1 | 3 525 318 | 336 172 | 3.90 (3.88 to 3.91) | 23 (0.23 to 0.23) | 93 (0.93 to 0.93) | 4 780 209 | 6.53 |
SI>1.2 | 2 227 378 | 252 465 | 4.73 (4.71 to 4.74) | 17 (0.17 to 0.18) | 96 (0.96 to 0.96) | 3 649 683 | 4.98 |
SI>1.3 | 1 397 331 | 185 698 | 5.67 (5.64 to 5.69) | 13 (0.13 to 0.13) | 97 (0.97 to 0.97) | 2 953 170 | 4.03 |
SI>1.4 | 820 675 | 130 857 | 7.02 (6.97 to 7.06) | 9 (0.09 to 0.09) | 98 (0.98 to 0.98) | 2 486 196 | 3.39 |
SI>1.5 | 91 528 | 527 334 | 7.77 (7.72 to 7.83) | 7 (0.07 to 0.07) | 99 (0.99 to 0.99) | 2 271 513 | 3.10 |
SI>1.6 | 67 044 | 338 731 | 9.13 (9.06 to 9.21) | 3 (0.03 to 0.04) | 99 (0.99 to 0.99) | 2 131 878 | 2.91 |
SI>1.7 | 48 146 | 213 091 | 10.80 (10.69 to 10.91) | 2 (0.02 to 0.03) | 99 (0.99 to 0.99) | 2 044 034 | 2.79 |
SI>1.8 | 38 838 | 156 976 | 12.17 (12.03 to 12.3) | 2 (0.02 to 0.02) | 99 (0.99 to 0.99) | 2 006 535 | 2.74 |
*n denotes the number of patient encounters included in the study in each specific SI category.
LR, likelihood ratio; SI, shock index.