Changes in biomarkers associated with fibrinolysis (median and IQR)
| Prehospital (IQR) | ED (IQR) | 2.5 hours (IQR) | 5 hours (IQR) | |
| tPA (AU/mL) | 41 (18–93) | 10 (3.5–40) | 2.8 (1.6–6.5) | 1.2 (0.3–3.7) |
| n | 51 | 52 | 50 | 46 |
| Imputed (<0.1=0.1) | 0 | 0 | 0 | 1 |
| Missing | 1 | 0 | 2 | 6 |
| PAI-1 (IU/mL) | 5.8 (3.7–9.1) | 11.2 (5.5–16.8) | 20.4 (13.6–33.0) | 36.0 (24.3–38.3) |
| N | 52 | 52 | 51 | 46 |
| Imputed (<0.1 = 0.1) | 26 | 15 | 5 | 0 |
| Missing | 0 | 0 | 1 | 6 |
| D-dimer (ng/mL) | 620 (390–1130) | 980 (530–1510) | 880 (360–1520) | 690 (340–1060) |
| N | 26 | 34 | 34 | 31 |
| Imputed (>200 = 200) | 2 | 4 | 6 | 3 |
| Missing | 26 | 18 | 18 | 21 |
ED, emergency department; PAI-1, plasminogen activator inhibitor 1; tPA, tissue plasminogen activator.