Diagnostic accuracy of clinical criteria to discriminate the presence of a raised ICP in subgroups of patients with isolated head injury (n=92) and code red patients (n=53)
| Sensitivity | Specificity | LR+ | LR− | AUC | |
| Isolated TBI | |||||
| Fixed pupils>5 mm or (HR <60 and SBP >160) | 38.3 (24.5–53.6) | 95.7 (85.2–99.5) | 8.8 (2.2–35.8] | 0.7 (0.5–0.8) | 0.66 (0.54–0.77) |
| Code red | |||||
| Fixed pupils>5 mm or (HR <60 and SBP >160) | 53.8 (25.1–80.8) | 95.0 (83.1–99.4) | 10.8 (2.6–45.5) | 0.5 (0.3–0.9) | 0.74 (0.56–92) |
| Fixed pupils>5 mm or (HR <70 and SBP >130) | 61.5 (31.6–86.2) | 87.5 (73.2–95.8) | 4.9 (2.0–12.4) | 0.4 (0.2–0.9) | 0.75 (0.57–0.92) |
AUC, Area Under the Curve; HR, heart rate; LR+, positive likelihood ratio; LR−, negative likelihood ratio; SBP, systolic blood pressure.