Abstract 100 Table 1

Participant characteristics

Variable	n = 70 n (%) or median [IQR]

Physiologic variables
Female	43 ( 61.4 )
Age	35 [ 26 – 47 ]
Heart rate (beats per minute)	130 [ 121 – 142 ]
Systolic blood pressure (mm Hg)	99 [ 86 – 115 ]
Systolic blood pressure ≤ 90 mm Hg	24 ( 34.3 )
Mean arterial pressure ≤ 65 mm Hg	15 ( 21.4 )
Respiratory rate (breaths per minute)	28 [ 22 – 36 ]
Oxygen saturation (%)	92 [ 86 – 96 ]
Oxygen saturation < 90%	30 ( 42.8 )
Whole blood lactate (mmol/L)	3.9 [ 2.6 – 7.2 ]
HIV-related variables
Unknown HIV serostatus at enrollment	2 ( 2.9 )
Negative HIV serostatus tested within 6 months	20 ( 28.6 )
Known positive HIV serostatus	48 ( 68.6 )
Time since HIV diagnosis (days) (n = 40)	537 [ 22 – 1972 ]
On antiretroviral therapy at enrollment	41/48 ( 85.4 )
Sepsis treatment variables
Cumulative amount of intravenous fluid given (mL)
Prior to enrollment	0 [ 0 – 1000 ]
By 3 hours after enrollment	1000 [ 200 – 1450 ]
By 6 hours after enrollment	1000 [ 500 – 2000 ]
By 24 hours after enrollment	1150 [ 1000 – 2000 ]
By 48 hours after enrollment	1900 [ 1000 – 2750 ]
By 72 hours after enrollment	2000 [ 1000 – 3000 ]
Cumulative number of participants who received empiric antibiotics (ceftriaxone, 2g intravenous)
Prior to enrollment	21 ( 30.0 )
By 3 hours after enrollment	47 ( 67.1 )
By 6 hours after enrollment	60/66 ( 90.9 )
By 24 hours after enrollment	65/66 ( 98.5 )
Baseline sonographic B-line score *	5 [ 2 – 8 ]
In- hospital mortality	17 ( 24.3 )