Patients without post-randomisation scans by baseline injury severity and treatment group
| Patients without post-randomisation scan (n=335/1767) | TXA group | Placebo group | RR (95% CI) | P value (two-tailed) | |
| Glasgow Coma Score (GCS) | |||||
| Mild (GCS 13 to 15) | 28 (8%) | 15/47 (32%) | 13/45 (29%) | 1.10 (0.59 to 2.06) | 0.75 |
| Moderate (GCS 9 to 12) | 106 (32%) | 53/264 (20%) | 53/267 (20%) | 1.01 (0.72 to 1.42) | 0.95 |
| Severe (GCS 3 to 8) | 201 (60%) | 101/573 (18%) | 100/570 (18%) | 1.00 (0.78 to 1.29) | 0.97 |
| Pupil reaction | |||||
| Both react | 224 (67%) | 108/637 (17%) | 116/651 (18%) | 0.95 (0.75 to 1.21) | 0.68 |
| One reacts | 28 (8%) | 14/97 (14%) | 14/105 (13%) | 1.08 (0.54 to 2.16) | 0.82 |
| None react | 75 (22%) | 42/124 (34%) | 33/108 (31%) | 1.11 (0.76 to 1.62) | 0.59 |
| Unable to assess | 8 (2%) | 5/25 (20%) | 3/18 (17%) | 1.20 (0.32 to 4.46) | 0.79 |
RR, relative risk; TXA, tranexamic acid.