Relationship between admission oxygen saturation group and inpatient mortality on univariate and multivariate analysis in patients receiving supplemental oxygen, with and without hypercapnia
| Died/ total | Univariate analysis | Multivariate analysis | |||||
| OR | 95% CI | P value | OR | 95% CI | P value | ||
| Normocapnia | N=50/476 | ||||||
| Oxygen saturations | |||||||
| 88%–92% | 9/139 | 1 | Reference | – | 1 | Reference | – |
| 97%–100% | 16/105 | 2.62 | 1.11 to 6.21 | 0.029 | 4.32 | 2.19 to 8.52 | <0.001 |
| 93%–96% | 17/184 | 1.47 | 0.63 to 3.41 | 0.373 | 2.31 | 1.17 to 4.58 | 0.016 |
| 87% or less | 8/47 | 2.93 | 1.06 to 8.14 | 0.039 | 2.08 | 1.01 to 4.25 | 0.046 |
| NEWS2-sats | – | – | – | 1.18 | 1.09 to 1.28 | <0.001 | |
| DECAF | – | – | – | 2.74 | 2.36 to 3.17 | <0.001 | |
| Hypercapnia | N=81/551 | ||||||
| Oxygen saturations | |||||||
| 88%–92% | 15/143 | 1 | Reference | – | 1 | Reference | – |
| 97%–100% | 22/118 | 1.90 | 0.93 to 3.90 | 0.079 | 2.28 | 0.99 to 5.21 | 0.052 |
| 93%–96% | 27/191 | 1.37 | 0.70 to 2.68 | 0.361 | 1.82 | 0.84 to 3.95 | 0.128 |
| 87% or less | 17/99 | 1.71 | 0.81 to 3.63 | 0.158 | 1.10 | 0.47 to 2.59 | 0.295 |
| NEWS2-sats | – | – | – | 1.26 | 1.12 to 1.43 | <0.001 | |
| DECAF | – | – | – | 2.27 | 1.78 to 2.90 | <0.001 | |
DECAF, dyspnoea, eosinopenia, chest X-ray consolidation, acidaemia, atrial fibrillation; NEWS2, National Early Warning Score.