Table 4

Patients with post-randomisation scans by baseline injury severity and treatment group

Patients with post-randomisation scan
(n=1431/1767)
TXA groupPlacebo groupRR (95% CI)P value
(two-tailed)
Glasgow Coma Score (GCS)
 Mild (GCS 13 to 15)64 (4%)32/47 (68%)32/45 (71%)0.96 (0.73 to 1.26)0.75
 Moderate (GCS 9 to 12)425 (30%)211/264 (80%)214/267 (80%)1.00 (0.92 to 1.09)0.95
 Severe (GCS 3 to 8)942 (66%)472/573 (82%)470/570 (82%)1.00 (0.95 to 1.05)0.97
Pupil reaction
 Both react1064 (74%)529/637 (83%)535/651 (82%)1.01 (0.96 to 1.06)0.68
 One reacts174 (12%)83/97 (86%)91/105 (87%)0.99 (0.88 to 1.10)0.82
 None react157 (11%)82/124 (66%)75/108 (69%)0.95 (0.80 to 1.14)0.59
 Unable to assess35 (2%)20/25 (80%)15/18 (83%)0.96 (0.72 to 1.28)0.78
  • RR, relative risk; TXA, tranexamic acid.