Demographics, mode of arrival, incidence of acute kidney injury, lactic acidaemia and 7-day inpatient mortality in acute medical admissions during the first 5 weeks of lockdown in comparison with previous years
| Prelockdown | COVID-19 lockdown | ||
| n=14 954 | n=1682 | ||
| Male sex, n (%) | 6803 (45.5) | 832 (49.5) | p<0.01* |
| Age, median (IQR) | 72 (26) | 69 (26) | p<0.001† |
| Emergency ambulance, no (%) | 5633 (37.7) | 892(53) | p<0.001* |
| SIMD quintile, n (%) | |||
| 1 | 2504 (16.7) | 305 (18.1) | p=0.09 |
| 2 | 4205 (28.1) | 441 (26.2) | |
| 3 | 2650 (17.7) | 278 (16.5) | |
| 4 | 2230 (14.9) | 280 (16.6) | |
| 5 | 3357 (22.4) | 377 (22.4) | |
| AKIN score 0–1, n (%) | 14 292 (95.6) | 1578 (93.8) | |
| AKIN score 2–3, n (%) | 662 (4.4) | 104 (6.2) | p<0.001‡ |
| Lactate, n (%) | |||
| Lactate ≤2.4 mmol/L | 13 864 (92.7) | 1473 (87.6) | |
| Lactate >2.4 mmol/L | 1090 (7.3) | 209 (12.4) | p<0.001‡ |
| 7-day inpatient mortality | 374 (2.5) | 71 (4.2) | p<0.001‡ |
Missing values for SIMD quintile: prelockdown 8 (0.1%); COVID-19 lockdown 1 (0.1%). Missing values for AKI (prelockdown 510 (3.4%), COVID-19 lockdown 38 (2.3%) and lactate (prelockdown 9782 (65.4%), COVID-19 lockdown 812 (48.3%) were combined with the AKIN score 0–1 group and lactate ≤2.4 mmol/L, respectively, as described in Methods.
*χ2 analysis
†Mann-Whitney U test.
‡Binary logistic regression.
AKIN, Acute Kidney Injury Network; SIMD, Scottish Index of Multiple Deprivation.