Table 1

Patient characteristics

All patients n=939HEART score ≤3 n=501HEART 0-hour/1-hour Pathway rule-out n=468EDACS 0-hour/1-hour ADP rule-out n=466
General information
 Age, years mean, SD60.6 (17.4)50.3 (15.5)49.5 (15.1)50.0 (15.4)
 Gender, male514 (54.7%)251 (50.1%)229 (48.9%)195 (41.8%)
 Arrival by ambulance386 (41.1%)134 (26.7%)119 (25.4%)124 (26.6%)
History of
 Myocardial infarction188 (20.0%)14 (2.8%)14 (3.0%)29 (6.2%)
 Stable angina197 (21.0%)17 (3.4%)14 (3.0%)26 (5.6%)
 CABG81 (8.6%)1 (0.2%)1 (0.2%)3 (0.6%)
 PCI164 (17.5%)18 (3.6%)18 (3.8%)27 (5.8%)
 Diabetes mellitus type 1 or 2134 (14.3%)17 (3.4%)16 (3.4%)29 (6.2%)
 Hypertension415 (44.2%)96 (19.2%)82 (17.5%)108 (23.2%)
 Stroke/TIA85 (9.1%)2 (0.4%)2 (0.4%)13 (2.8%)
Other risk factors
 Current smoker122 (13.0%)73 (14.6%)68 (14.5%)71 (15.2%)
 Family history of CAD*226 (24.1%)117 (23.4%)114 (24.4%)127 (27.3%)
 BMI, mean, SD27.0 (7.5)26.3 (6.3)26.3 (6.4)26.6 (6.6)
Current medications
 Aspirin/ADP inhibitor274 (29.2%)46 (9.2%)41 (8.8%)65 (13.9%)
 ACE/ARB blocker295 (31.4%)57 (11.4%)49 (10.5%)69 (14.8%)
 Beta blocker288 (30.7%)59 (11.8%)50 (10.7%)69 (14.8%)
 Nitrates219 (23.3%)28 (5.6%)27 (5.8%)44 (9.4%)
 Statins279 (29.7%)38 (7.6%)35 (7.5%)69 (14.8%)
Clinical findings
 Mean systolic BP, mm Hg (SD)145 (24.2)141 (21.5)140 (20.6)141 (21.8)
 Mean diastolic BP, mm Hg (SD)85 (14.1)85 (13.9)85 (13.5)86 (13.4)
 ECG showing signs of acute ischaemia63 (6.7%)3 (0.6%)3 (0.6%)0
MACE within 30 days
 Final diagnosis of index visit myocardial infarction75 (8.0%)4 (0.8%)01 (0.2%)
 Total MACE (including unstable angina)116 (12.4%)6 (1.2%)1 (0.2%)4 (0.9%)
 All cause death within 30 days4 (0.4%)1 (0.2%)00
  • Values are mean (SD) or n (%).

  • *Defined as close relative with AMI, angina or cardiac death before the age of 55 years.

  • ACS, acute coronary syndrome; ADP, accelerated diagnostic protocol; ADP inhibitor, adenosine diphosphate receptor inhibitor; ARB blocker, angiotensin II receptor blocker; CABG, coronary artery bypass graft; MACE, major adverse cardiovascular events; PCI, percutaneous coronary intervention; TIA, transitory ischaemic attack.