Table 3

Univariate analysis of baseline, clinical and laboratory characteristics recorded on ED admissions of patients with SARS-CoV-2 infection distributed according to death within 30 days of ED evaluation

AliveDeathP value
Patients, n (%)242 (81.8)54 (18.2)
Serum albumin (g/dL), mean (SD)3.8 (0.5)3.3 (0.4)<0.001*
Serum albumin
 Albumin <3.5 g/dL, n (%)79 (32.6)40 (74.1)<0.001†
 Albumin <3.0 g/dL, n (%)18 (7.4)12 (22.2)0.006†
Age, years, mean (SD)65 (16)82 (9)<0.001*
Gender, n (%)0.876†
 Male156 (64.5)34 (63.0)
 Female86 (35.5)20 (37.0)
Comorbidity, n (%)
 At least one chronic disease157 (64.9)53 (98.1)<0.001†
 Two or more chronic diseases97 (40.1)43 (79.6)<0.001†
Temperature on arrival in ED (°C) mean (SD)37.3 (0.9)37.4 (0.9)0.507‡
Clinical condition on arrival in ED
 Altered mental status, n (%)18 (7.4)19 (35.2)<0.001†
 Respiratory rate (breaths per minute) >3024 (9.9)20 (37.0)<0.001†
 Oxygen saturation (%) <93%105 (43.4)48 (88.9)<0.001†
Laboratory findings, median (IQR)
 Haemoglobin (g/dL)14.1 (12.7–15.2)13.4 (11.9–14.7)0.094‡
 Haematocrit (%)42.6 (38.9–45.1)41.0 (36.5–45.1)0.151‡
 Leucocytes (×1000/µL)6.2 (4.9–8.4)7.1 (5.1–9.5)0.250‡
 Platelets counts (×1000/µL)205 (160–266)173 (137–225)0.003‡
 Creatinine (mg/dL)0.9 (0.8–1.1)1.2 (0.9–1.9)<0.001‡
 Glomerular filtration rate (mL/min/1.73)80 (59–93)46 (30–68)<0.001‡
 C reactive protein (mg/dL)5.2 (1.9–10.3)11.1 (6.5–17.5)<0.001‡
Leucocytes, median (IQR)
 Neutrophil (×1000/µL)
4.38 (3.15–6.32)5.98 (3.50–8.35)0.020‡
 Lymphocytes (×1000/µL)1.07 (0.74–1.50)0.75 (0.48–1.30)<0.001‡
 Monocytes (×1000/µL)0.52 (0.34–0.72)0.38 (0.27–0.62)0.006‡
Liver function, median (IQR)
 Alanine aminotransferase (U/L)30 (21–47)32 (22–43)0.369‡
 Aspartate aminotransferase (U/L)36 (25–52)43 (30–63)0.101‡
  • *Student’s t-test.

  • †Fisher’s exact test.

  • ‡Mann-Whitney test.