Outcome | Author, year, reference | qSOFA AUROC (95% CI) | NEWS AUROC (95% CI) | Mews AUROC (95% CI) | Measured mortality |
ICU admission | Goulden et al, 201820 | 0.59 (0.52 to 0.67) | 0.64 (0.57 to 0.71) | – | |
Churpek et al, 201721 | 0.62* (0.60 to 0.63) | 0.72* (0.70 to 0.73) | 0.68* (0.66 to 0.70) | ||
Samsudin et al, 201824 | 0.63† (0.541 to 0.715) | 0.70† (0.622 to 0.784) | 0.61 (0.517 to 0.699) | ||
de Groot et al, 201725 | 0.72‡ (0.68 to 0.75) | 0.75‡ (0.72 to 0.79) | 0.71‡ (0.68 to 0.75) | ||
Redfern et al, 201826 | 0.675§ (0.668 to 0.681) | 0.791§ (0.785 to 0.796) | – | ||
Martino et al, 201829 | 0.61 (0.5 to 0.73) | – | 0.66 (0.54 to 0.78) | ||
Mortality | Goulden et al, 201820 | 0.62 (0.59 to 0.66) | 0.65 (0.61 to 0.68) | – | In-hospital mortality |
Churpek et al, 201721 | 0.71¶ (0.68 to 0.72) | 0.80¶ (0.78 to 0.82) | 0.75¶ (0.73 to 0.76) | In-hospital mortality | |
Usman et al, 201822 | 0.79 (NG) (0.87) | 0.88 (NG) (0.95) | – | In-hospital mortality (sepsis-related mortality) | |
Szakmany et al, 201823 | 0.57 (0.49 to 0.64) | 0.59 (0.51 to 0.66) | – | 30-day all-cause mortality | |
Samsudin et al, 201824 | 0.65 (0.557 to 0.741) | 0.70 (0.615 to 0.788) | 0.56 (0.462 to 0.659) | 30-day in-hospital mortality | |
de Groot et al, 201725 | 0.68 (0.63 to 0.72) | 0.67 (0.62 to 0.72) | 0.63 (0.58 to 0.67) | In-hospital mortality | |
Redfern et al, 201826 | 0.675 (0.668 to 0.682) | 0.79 (0.784 to 0.796) | – | In-hospital mortality | |
Redondo-González et al, 201827 | 0.67 (0.58 to 0.76) | 0.73 (0.65 to 0.81) | – | In-hospital mortality | |
Innocenti et al, 201728 | 0.625 (0.579 to 0.671) | – | 0.662 (0.618 to 0.705) | 28-day mortality | |
Martino et al, 201829 | 0.75 (0.67 to 0.84) | – | 0.74 (0.66 to 0.83) | In-hospital mortality | |
Liu and Hu, 201830 | 0.657 (0.617 to 0.695) | – | 0.628 (0.587 to 0.667) | 28-day mortality | |
Brink et al, 201932 | 0.697 (0.667 to 0.726) | 0.779 (0.755 to 0.804) | – | 30-day mortality |
*Composite outcome of mortality and ICU admission. Taken ED only data from paper for this.
†Composite outcome of in-hospital mortality, ICU admission and intubation within 30 days of ED admission.
‡This paper included both ICU/MCU admission together.
§Taken ED data only, ICU admission OR in-hospital mortality.
¶Taken ED data only.
AUROC, Area under the Receiver Operating Characteristic Curve; ED, emergency department; ICU, intensive care unit; MCU, medium care unit; MEWS, Modified Early Warning Score; NEWS, National Early Warning Score; NG, not given; qSOFA, Quick Sequential(Sepsis-related)Organ Failure Assessment.