Table 1

Baseline characteristics

VariablesNSuspected sepsis
No of patients, n (%)509509 (100)
Age (years), median (IQR)50974.0 (58.0–82.0)
Female gender, n (%)509246 (48.3)
Method of arrival, n (%)509
 Ambulance509415 (81.5)
 General practitioner referral50927 (5.3)
 Self-presented50962 (12.2)
 Community team referral5093 (0.6)
 Outpatient clinic referral5091 (0.2)
 Police transport5091 (0.2)
Location within the ED, n(%)
 Resuscitation room509228 (44.8)
 Majors509171 (33.6)
 Minors5094 (0.8)
 Majors transferred to resuscitation room50921 (4.1)
 Resuscitation room transferred to majors5092 (0.4)
 Not documented50983 (16.3)
Initial emergency department observations, mean±SD or median (IQR)
 RR (breaths per minute)
 (first available RR used)*
507
(509)
22.9±6
(22.4±6)
 HR (beats per minute) 509 105.7±23.4
 Systolic BP (mm Hg)
 (first available SBP used)*
506
(509)
126.5±29.9
(126.4±29.9)
 Diastolic BP (mm Hg)
 (first available dBP used)*
506
(509)
70.2±16.2
(70.2±16.3)
 Mean arterial pressure (mm Hg)
 (first available BP used)*
506
(509)
89.0±19.26
(88.9±19.29)
 Saturations (%)
 (first available saturation used)*
501
(509)
95.3±3.9
(95.2±3.9)
 FiO2
 (first available FiO2 used)*
506
(508)
0.21 (0.21–0.35)
(0.21 (0.21–0.35)
 Temperature (oC)
 (first available temperature used)*
502
(508)
37.7±1.2
(37.7±1.2)
 GCS
 (first available GCS used)*
478
(506)
15(14-15)
(15(14-15))
qSOFA ≥2, n(%)
Missing values considered as 0 points509132 (25.9)
First available values used509139 (27.3)
NEWS, median (IQR)
Missing values considered as 0 points5096 (3–8)
First available values used5096 (3–8)
Change in SOFA score, median (IQR)5092 (0–3)
Change in SOFA ≥2, n(%)509256 (50.3)
Definitive infection and change of SOFA ≥2, n(%)509251 (49.3)
  • *If the first value was missing, the next recorded value was used.

  • BP, blood pressure; ED, emergency department; FiO2, fraction of inspired oxygen; GCS, Glasgow Comma Scale; HR, heart rate; NEWS, National Early Warning Score; qSOFA, quick Sequential Organ Failure Assessment; RR, respiratory rate; SOFA, Sequential Organ Failure Assessment.