Table 3

Comorbidities, CCI and medication

VariablesSuspected sepsis (n=509)
Comorbidity, n (%)
No comorbidities*55 (10.8)
 Pulmonary disease156 (30.6)
  COPD105 (20.6)
 Hypertension143 (28.1)
 Diabetes Mellitus143 (28.1)
  End-organ damage20 (3.9)
 Ischaemic heart disease98 (19.3)
Chronic kidney disease98 (19.3)
  CCI criteria moderate to severe CKD21 (4.1)
 Solid tumour (all)91 (17.9)
  Metastatic30 (5.9)
 CVA or TIA80 (15.7)
 Atrial fibrillation75 (14.7)
 Dementia75 (14.7)
 Congestive heart failure61 (12.0)
 Connective tissue disease27 (5.3)
 Peripheral vascular disease25 (4.9)
 Haematological malignancy17 (3.3)
 Liver disease (all)11 (2.2)
  Moderate to severe8 (1.6)
 Peptic ulcer disease10 (2.0)
CCI score, median (IQR)5 (2–6)
Immunosuppressant medication, n(%)
 LT steroids47 (9.2)
 Chemotherapy19 (3.7)
 Other (DMARDs, antiproliferative medication, calcineurin inhibitors)23 (4.5)
 None424 (83.3)
 Not documented8 (1.6)
  • *0 CCI score.

  • CCI, Charlson Comorbidity Index; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; CVA, cerebrovascular accident; DMARDs, disease-modifying antirheumatic drugs; LT, long term; TIA, transient ischaemic attack.