Comorbidities, CCI and medication
| Variables | Suspected sepsis (n=509) |
| Comorbidity, n (%) | |
| No comorbidities* | 55 (10.8) |
| Pulmonary disease | 156 (30.6) |
| COPD | 105 (20.6) |
| Hypertension | 143 (28.1) |
| Diabetes Mellitus | 143 (28.1) |
| End-organ damage | 20 (3.9) |
| Ischaemic heart disease | 98 (19.3) |
| Chronic kidney disease | 98 (19.3) |
| CCI criteria moderate to severe CKD | 21 (4.1) |
| Solid tumour (all) | 91 (17.9) |
| Metastatic | 30 (5.9) |
| CVA or TIA | 80 (15.7) |
| Atrial fibrillation | 75 (14.7) |
| Dementia | 75 (14.7) |
| Congestive heart failure | 61 (12.0) |
| Connective tissue disease | 27 (5.3) |
| Peripheral vascular disease | 25 (4.9) |
| Haematological malignancy | 17 (3.3) |
| Liver disease (all) | 11 (2.2) |
| Moderate to severe | 8 (1.6) |
| Peptic ulcer disease | 10 (2.0) |
| CCI score, median (IQR) | 5 (2–6) |
| Immunosuppressant medication, n(%) | |
| LT steroids | 47 (9.2) |
| Chemotherapy | 19 (3.7) |
| Other (DMARDs, antiproliferative medication, calcineurin inhibitors) | 23 (4.5) |
| None | 424 (83.3) |
| Not documented | 8 (1.6) |
*0 CCI score.
CCI, Charlson Comorbidity Index; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; CVA, cerebrovascular accident; DMARDs, disease-modifying antirheumatic drugs; LT, long term; TIA, transient ischaemic attack.