Triage tool diagnostic accuracy statistics (95% CI) for predicting any adverse outcome
Tool | N* | n (%) adverse outcome† | C-statistic | Threshold | n (%) above threshold | Sensitivity | Specificity | PPV | NPV |
CRB-65 | 7469 | 1315 (18) | 0.79 (0.78 to 0.80) | >0 | 4010 (54) | 0.89 (0.88 to 0.89) | 0.54 (0.53 to 0.54) | 0.29 (0.29 to 0.30) | 0.96 (0.95 to 0.96) |
NEWS2 | 7433 | 1315 (18) | 0.80 (0.78 to 0.81) | >1 | 5574 (75) | 0.96 (0.96 to 0.96) | 0.30 (0.29 to 0.30) | 0.23 (0.22 to 0.23) | 0.97 (0.97 to 0.97) |
PMEWS | 7460 | 1315 (18) | 0.81 (0.80 to 0.83) | >2 | 5352 (72) | 0.98 (0.97 to 0.98) | 0.34 (0.33 to 0.34) | 0.24 (0.24 to 0.24) | 0.99 (0.98 to 0.99) |
PRIEST | 7471 | 1315 (18) | 0.83 (0.82 to 0.84) | >4 | 4932 (66) | 0.97 (0.97 to 0.97) | 0.41 (0.40 to 0.41) | 0.26 (0.25 to 0.26) | 0.98 (0.98 to 0.99) |
WHO | 7471 | 1315 (18) | 0.64 (0.64 to 0.65) | >0 | 5539 (74) | 0.98 (0.97 to 0.98) | 0.31 (0.30 to 0.31) | 0.23 (0.23 to 0.24) | 0.98 (0.98 to 0.99) |
*Patients with less than three parameters were excluded from analysis when estimating performance.
†Totals rounded to nearest 5.
NEWS2, National Early Warning Score, version 2; NPV, negative predictive value; PPV, positive predictive value.