Results from diagnostic accuracy studies of POCT hs-cTn assays at presentation for the diagnosis of AMI
| POC assay | AUC (95% CI) | Comparator assay | AUC (95% CI) | Patients | AMI rate |
| PATHFAST POC hs-cTnI7
(plasma) | 0.91 (0.89 to 0.93) | cTnI-Architect (fresh serum or plasma) | 0.90 (0.87 to 0.92) | 1279 | 134 (20%) |
| i-STAT TnI-Nx20 * (plasma) | 0.97 (0.96 to 0.99) | cTnI-Architect (plasma) | 0.97 (0.95 to 0.99) | 354 | 57 (16%) |
| Minicare POC hs-cTnI9
(whole blood) | 0.88 (0.83 to 0.94) | cTnI-Architect (serum or plasma) | 0.91 (0.87 to 0.95) | 450 | 72 (16%) |
| I-Stat POC cTnI | 0.88 (0.82 to 0.94) | ||||
| Triage True POC hs-cTnI6
(plasma) | 0.95 (0.93 to 0.96) | cTnT Elecsys (serum or plasma) | 0.94 (0.93 to 0.96) | 1261 | 178 (14%) |
| cTnI-Architect (serum or plasma) | 0.92 (0.90 to 0.93) |
*Analytical studies of this assay are pending.
AMI, acute myocardial infarction; AUC, area under the curve; hs-cTnI, high-sensitivity cardiac troponin I; POCT, point-of-care test.