Table 2

Overview of diagnostic characteristics of all conclusive sonographies

N totalN conclusive (% of total)Sensitivity
(95% CI)
Specificity
(95% CI)
PPV*
(95% CI)
NPV*
(95% CI)
LR+
(95% CI)
LR−
(95% CI)
N inconclusive (% of total)
Overall 50830889.6 (82.1 to 94.3)93.8 (89.1 to 96.6)87.98 (80.84 to 92.71)94.65 (91.18 to 96.80)14.4 (8.3 to 25.01)0.11 (0.06 to 0.19)200
Radiologists16687(52.4)90.32 (74.25 to 97.96)91.07 (80.38 to 97.04)83.72 (68.85 to 92.29)94.88 (86.29 to 98.20)10.12 (4.35 to 25.54)0.11 (0.04 to 0.31)79 (47.6)
ED physicians overall342221(64.6)89.29 (80.63 to 94.98)94.89 (89.76 to 97.92)89.88 (81.13 to 94.83)94.57 (90.37 to 97.0)17.47 (8.46 to 36.1)0.11 (0.06 to 0.21)121 (35.4)
Advanced ED sonographers154†117(75.97)90.91 (78.33 to 97.47)94.52 (86.56 to 98.49)89.4 (76.4 to 95.65)95.34 (88.92 to 98.12)16.59 (6.37 to 43.22)0.1 (0.04 to 0.25)37 (24.03)
Unexperienced ED sonographers81†39(48.15)87.50 (61.65 to 98.45)91.3 (71.96 to 98.93)83.65 (57.32 to 95.12)93.49 (79.62 to 98.14)10.06 (2.64 to 38.32)0.14 (0.04 to 0.5)42 (51.85)
  • *Based on an overall prevalence of appendicitis in this study of 33.7%.

  • †Examiner experience missing for 107 exams.

  • LR+, positive likelihood ratio; LR−, negative likelihood ratio; NPV, negative predictive value; PPV, positive predictive value.