Diagnostic performance of MACS-ECG
| Original cut-off | Original cut-off | Optimised cut-off |
| Sensitivity (95% CI) | 2.3% (0.28% to 8.06%) | 50.57% (39.6% to 61.5%) |
| Specificity (95% CI) | 99.5% (98.6% to 99.9%) | 83.11% (79.9% to 86.0%) |
| NPV (95% CI) | 87.6% (87.3% to 88.0%) | 92.1% (90.4% to 93.5%) |
| PPV (95% CI) | 40.0% (10.2% to 79.7%) | 30.1% (24.7% to 36.2%) |
Original cut-off: predicted probability for NSTEMI of 27.4%.
Optimised cut-off: predicted probability for NSTEMI of 9.56% AMI.
AMI, acute myocardial infraction; MACS-ECG, Manchester Acute Coronary Syndromes ECG; NPV, negative predictive value; NSTEMI, non-ST elevation myocardial infarction; PPV, positive predictive value.