Research LettersAdverse events of premixed nitrous oxide and oxygen for procedural sedation in children
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The Role of Nitrous Oxide in Minor Pediatric Procedures in the Emergency Department: A Systematic Review
2024, Journal of Pediatric SurgerySevere hyperhomocysteinemia and peripheral neuropathy as side effects of nitrous oxide in two patients with sickle cell disease
2019, Archives de PediatrieCitation Excerpt :Major side effects associated with N2O use include oxygen desaturation, airway obstruction, bradycardia, and oversedation, with a 0.33% rate of potentially life-threatening events in a prospective study. Benign and transient side effects (nausea, vomiting, dizziness or paresthesias) were also reported [4]. Bone marrow suppression with chronic use, as in patient 1, is also a known side effect of N2O [1].
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2019, Annals of Physical and Rehabilitation MedicineImproving Stakeholder Satisfaction: Nitrous Oxide for Peripheral Intravenous Cannulation for Pediatric Procedural Sedation
2017, Journal of Radiology NursingPractice Patterns and Adverse Events of Nitrous Oxide Sedation and Analgesia: A Report from the Pediatric Sedation Research Consortium
2016, Journal of PediatricsCitation Excerpt :First, patients usually received a concomitant opioid or benzodiazepine, although the vast majority of patients who received such medications did so without serious adverse events.6,8,21 Second, the serious adverse events reported consisted almost exclusively of oxygen desaturations or airway obstruction, similar to what was observed in our study.1,6,8-11,13,21,23,33 There has only been 1 episode of cardiac arrest reported with N2O in this context, which was linked to both inappropriate use of the administration device and insufficient surveillance.21