THE FIRST SEIZURE IN ADULT LIFE: Value of Clinical Features, Electroencephalography, and Computerised Tomographic Scanning in Prediction of Seizure Recurrence

doi:10.1016/S0140-6736(88)91535-8

The Lancet

Volume 331, Issue 8588, 2 April 1988, Pages 721-726

https://doi.org/10.1016/S0140-6736(88)91535-8 Get rights and content

Abstract

408 adults (age 16 and over) were followed up after their initial seizure. The actuarial risk of recurrence was highest in the early weeks. For those seen within the first week, the risk of recurrence was 52 % by the end of 3 years. In univariate analysis, the only clinical variable that was associated with recurrence was the time of day at which the initial seizure occurred. There was a tendency, that did not reach statistical significance, for younger age ( < 50 years) and a family history of seizures of any type, including febrile convulsions, to be associated with recurrence. Such risk factors appear to be additive, so that the risk of recurrence at 1 year for a subject with all three factors is about three times that of a subject with none of them. Sex, type of seizure, and features of the electroencephalogram were not of predictive value. Computerised tomographic scanning revealed tumours in 3% of subjects, and these individuals were particularly likely to have recurrent seizures.

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THE FIRST SEIZURE IN ADULT LIFE: Value of Clinical Features, Electroencephalography, and Computerised Tomographic Scanning in Prediction of Seizure Recurrence

Abstract

Lancet

Lancet

Lancet

Lancet

Lancet

Epidemiology and the genetics of epilepsy

Epileptic seizures in a population of 6,000 Demography, diagnosis and classification and the role of the hospital services

Br Med J

The epidemiology of epilepsy in Rochester, Minnesota, 1935 through 1967

Epilepsia

The teratogenic associations of epilepsy and anticonvulsant drugs

Risk of recurrence after an initial unprovoked seizure

Epilepsia

BMDP statistical software, 1983 printing with additions

A glossary of terms most commonly used by electroencephalographers

Electroenceph Clin Neurophysiol

Binomial regression m GLIM: estimating risk ratios and risk differences

Am J Epidemiol

Epilepsy. In: Medical aspects of fitness to drive

Incidence of epilepsy in children: a follow up study three years after the first seizure

Epilepsia