Original contributionExperimental design for study of cardiopulmonary resuscitation in dogs
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Cited by (50)
Extracorporeal cardiopulmonary resuscitation (eCPR) and cerebral perfusion: A narrative review
2023, ResuscitationCitation Excerpt :It remains to be determined whether general patterns of post-ROSC cerebral perfusion are relevant for the eCPR patient in which flow is rapidly restored by VA-ECMO after a prolonged period of CPR. For example, eCPR is often preceded by up to 60 minutes of chest compressions which confer only 15-30% of normal cardiac output.14,15 Lactic acidosis and arterial pressure of carbon dioxide (PaCO2) progressively increase during prolonged CPR times despite utilization of an automatic chest compression device.14
Extracorporeal cardiopulmonary resuscitation for refractory cardiac arrest: A multicentre experience
2017, International Journal of CardiologyCitation Excerpt :Despite having a trend towards increased survival with times ≤ 60 min it did not reach significance. With effective conventional CPR, only 25–30% of cardiac output is delivered [30], in contrast the initiation of ECMO provides effective coronary and organ perfusion. Shortening time to ECMO flow should become akin to the key performance indicator used in primary angioplasty of “door to balloon” time.
A tourniquet assisted cardiopulmonary resuscitation augments myocardial perfusion in a porcine model of cardiac arrest
2015, ResuscitationCitation Excerpt :Both experimental and clinical studies have consistently demonstrated that the success of resuscitation during CPR is largely dependent on the efficacy of cardiac output generated by chest compression.2–5 However, cardiac output and myocardial perfusion generated by conventional CPR rarely exceeds 30% and 50% of normal levels, respectively.6,7 In addition, cardiac output gradually decreases during prolonged CPR in spite of continuous precordial compression.8
Estimation of anatomical structures underneath the chest compression landmarks in children by using computed tomography
2011, ResuscitationCitation Excerpt :The blood flow during CPR is generated by the increased intrathoracic pressure resulting from chest compression or the direct compression of the heart.1–5 Cardiac output generated by CPR is 17–27% of that under normal conditions.6–9 For the improvement of the haemodynamic effect, many researchers have tried to find the optimal depth, rate of chest compression, and the ideal compression–ventilation ratio.10,11
Extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest: A review of the Japanese literature
2011, ResuscitationCitation Excerpt :In general, the pump can immediately generate sufficient blood flow in adult patients after the introduction of the artificial circulation. On the other hand, closed chest compression results in a cardiac output of 25–30% of normal when performed under optimal conditions.1 Thus, cerebral blood flow may be adequately maintained during ECPR, and may be one of the reasons for a good neurological outcome in patients receiving ECPR.
Presented at the University Association for Emergency Medicine Annual Meeting in Tucson, Arizona, April 1980.