Comparison of Binax NOW and Directigen for rapid detection of influenza A and B
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Acknowledgements
The expert technical assistance of the Clinical Virology Laboratory staff is greatly appreciated.
References (14)
- Anonymous, Rapid diagnostic tests for influenza. Med Lett Drugs Ther...
- et al.
Evaluation of a rapid optical immunoassay for influenza viruses (FLU OIA test) in comparison with cell culture and reverse transcription-PCR
J Clin Microbiol
(2001) - et al.
Impact of the rapid diagnosis of influenza on physician decision-making and patient management in the pediatric emergency department: results of a randomized, prospective, controlled trial
Pediatrics
(2003) - CDC update: influenza-associated deaths reported among children aged < 18 years–United States, 2003–04 influenza...
- et al.
Evaluation of the Directigen Flu A+B test for rapid diagnosis of influenza virus type A and B infections
J Clin Microbiol
(2002) Prevention and treatment of influenza
N Engl J Med
(2000)- et al.
Clinical evaluation of the ZstatFlu-II test: a chemiluminescent rapid diagnostic test for influenza virus
J Clin Microbiol
(2002)
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Laboratory diagnosis of viral infection
2014, Handbook of Clinical NeurologyBinaxNOW® - An immunochromatographic test for the diagnosis of human influenza viruses: Comparison with viral culture and polymerase chain reaction
2011, Indian Journal of Medical MicrobiologySevere H1N1-associated acute respiratory distress syndrome: A case series
2010, American Journal of MedicineCitation Excerpt :The majority of our patients had initial falsely negative rapid antigen tests, highlighting the limitations of this technique. At our institution, the rapid test has a sensitivity of 51%-80% and a specificity of 93%-100%,14 which are comparable with reported test characteristics from other institutions.15 Thus, a high index of clinical suspicion remains paramount, and the use of PCR testing may assist in confirming the diagnosis but should not delay empiric treatment.
Developments in Immunologic Assays for Respiratory Viruses
2009, Clinics in Laboratory MedicineCitation Excerpt :In contrast to ELISA, with LFIC the sample is simply added to the strip, or the test strip is inserted into the sample solution, and the timer is set. Yet performance is similar to membrane ELISA.30,31 For optimal performance, it is essential that the manufacturer's instructions for sample type, collection device, and preparation are carefully followed.
Performance of Binax NOW Flu A and B and direct fluorescent assay in comparison with a composite of viral culture or reverse transcription polymerase chain reaction for detection of influenza infection during the 2006 to 2007 season
2008, Diagnostic Microbiology and Infectious DiseaseCitation Excerpt :Although we did not observe a statistically significant difference in test sensitivity in children versus adults, the relatively high sensitivity in children is consistent with previously published results (Landry et al., 2004; Weinberg and Walker, 2005; Fader, 2005; Hurt et al., 2007). A decrease in sensitivity in adult patients has also been observed with other enzyme immunoassay rapid tests for detecting influenza infections (Yamazaki et al., 2000; Chan et al., 2002; Reina et al., 2002; Cazacu et al., 2003; Hamilton et al., 2002; Ruest et al., 2003; Cazacu et al., 2004; Landry et al., 2004; Alexander et al., 2005). Higher viral excretion by children has been suggested as a possible mechanism for higher sensitivity in children (Landry et al., 2000).
Real-time PCR compared to Binax NOW and cytospin-immunofluorescence for detection of influenza in hospitalized patients
2008, Journal of Clinical Virology