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Local Peritoneal Responses in Peritonities—Clinical Scenarios I: Peritoneal Compartment responses and its clinical consequences

  • Published:
Sepsis

Abstract

It is conceivable to view the peritoneal cavity as a separate and specialized compartment. Any events, which occur within this compartment are initially “compartmentalized,” but subsequently produce immense pathophysiological changes in the neighboring spaces and organs, and on the whole body as well. This review will focus on the local and systemic consequences of physical changes within the peritoneal compartment, caused by elevated intra-abdominal pressure and the pneumoperitoneum, which is induced during laparoscopic surgery. Intra-abdominal hypertension is yet another factor to consider in the overall management of the surgical and critically ill. Commonly it is relatively silent but contributing to patients SIRS, organ dysfunction and death. It may mimic sepsis and/or contribute to it. This old-new pathophysiological entity, which has been ignored for so long should be recognized, prevented and treated.

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Authors and Affiliations

  1. Department of Surgery, New York Methodist Hospital and Cornell University, Medical College, New York

    Moshe Schein & Adam Klipfel

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  1. Moshe Schein
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  2. Adam Klipfel
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Schein, M., Klipfel, A. Local Peritoneal Responses in Peritonities—Clinical Scenarios I: Peritoneal Compartment responses and its clinical consequences. Sepsis 3, 327–333 (1999). https://doi.org/10.1023/A:1009861629215

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  • DOI: https://doi.org/10.1023/A:1009861629215

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