Background The role of intensive insulin therapy in patients with severe sepsis is uncertain.
Fluid resuscitation improves survival among patients with septic shock, but evidence is …

ContextAnemia is a common problem in critically ill patients admitted to intensive care units
(ICUs), but the consequences of anemia on morbidity and mortality in the critically ill is …

Objective Measurement of extravascular lung water (EVLW) as a clinical tool for the
assessment of pulmonary function has been found to be more appropriate than oxygenation …

Objective: Sepsis is associated with an increase in reactive oxygen species and low
endogenous antioxidative capacity. We postulated that high-dose supplementation of …

Importance High-dose intravenous administration of sodium selenite has been proposed to
improve outcome in sepsis by attenuating oxidative stress. Procalcitonin-guided …

Context Early appropriate antimicrobial therapy leads to lower mortality rates associated
with severe sepsis. The role of empirical combination therapy comprising at least 2 …

Objective We report on the effect of hemoadsorption therapy to reduce cytokines in septic
patients with respiratory failure. Methods This was a randomized, controlled, open-label …

Importance Adjunctive hydrocortisone therapy is suggested by the Surviving Sepsis
Campaign in refractory septic shock only. The efficacy of hydrocortisone in patients with …

Epinephrine impairs splanchnic perfusion in septic shock : Critical Care Medicine Epinephrine
impairs splanchnic perfusion in septic shock : Critical Care Medicine SCCM Pediatric Critical …

Objective In septic shock, decreased splanchnic blood flow is reported, despite adequate
systemic hemodynamics. N-acetylcysteine (NAC) was found to increase hepatosplanchnic …