Hidden dynamics in the unfolding of individual bacteriorhodopsin proteins
H Yu, MGW Siewny, DT Edwards, AW Sanders… - Science, 2017 - science.org
Protein folding occurs as a set of transitions between structural states within an energy
landscape. An oversimplified view of the folding process emerges when transiently …
landscape. An oversimplified view of the folding process emerges when transiently …
Optimizing force spectroscopy by modifying commercial cantilevers: Improved stability, precision, and temporal resolution
DT Edwards, TT Perkins - Journal of structural biology, 2017 - Elsevier
Atomic force microscopy (AFM)-based single-molecule force spectroscopy (SMFS) enables
a wide array of studies, from measuring the strength of a ligand–receptor bond to elucidating …
a wide array of studies, from measuring the strength of a ligand–receptor bond to elucidating …
[PDF][PDF] Determining the oligomeric structure of proteorhodopsin by Gd3+-based pulsed dipolar spectroscopy of multiple distances
DT Edwards, T Huber, S Hussain, KM Stone… - Structure, 2014 - cell.com
The structural organization of the functionally relevant, hexameric oligomer of green-
absorbing proteorhodopsin (G-PR) was obtained from double electron-electron resonance …
absorbing proteorhodopsin (G-PR) was obtained from double electron-electron resonance …
Pulsed electron paramagnetic resonance spectroscopy powered by a free-electron laser
S Takahashi, LC Brunel, DT Edwards, J Van Tol… - Nature, 2012 - nature.com
Electron paramagnetic resonance (EPR) spectroscopy interrogates unpaired electron spins
in solids and liquids to reveal local structure and dynamics; for example, EPR has elucidated …
in solids and liquids to reveal local structure and dynamics; for example, EPR has elucidated …
Optimizing 1-μs-resolution single-molecule force spectroscopy on a commercial atomic force microscope
DT Edwards, JK Faulk, AW Sanders, MS Bull… - Nano …, 2015 - ACS Publications
Atomic force microscopy (AFM)-based single-molecule force spectroscopy (SMFS) is widely
used to mechanically measure the folding and unfolding of proteins. However, the temporal …
used to mechanically measure the folding and unfolding of proteins. However, the temporal …
Rapid characterization of a mechanically labile α-helical protein enabled by efficient site-specific bioconjugation
…, MA LeBlanc, WJ Van Patten, DT Edwards… - Journal of the …, 2017 - ACS Publications
Atomic force microscopy (AFM)-based single-molecule force spectroscopy (SMFS) is a
powerful yet accessible means to characterize mechanical properties of biomolecules …
powerful yet accessible means to characterize mechanical properties of biomolecules …
Effect of electron spin dynamics on solid-state dynamic nuclear polarization performance
…, A Lund, A Latimer, SA Walker, DT Edwards… - Physical Chemistry …, 2014 - pubs.rsc.org
For the broadest dissemination of solid-state dynamic nuclear polarization (ssDNP)
enhanced NMR as a material characterization tool, the ability to employ generic mono …
enhanced NMR as a material characterization tool, the ability to employ generic mono …
[PDF][PDF] Force spectroscopy with 9-μs resolution and sub-pN stability by tailoring AFM cantilever geometry
DT Edwards, JK Faulk, MA LeBlanc, TT Perkins - Biophysical journal, 2017 - cell.com
Atomic force microscopy (AFM)-based single-molecule force spectroscopy (SMFS) is a
powerful yet accessible means to characterize the unfolding/refolding dynamics of individual …
powerful yet accessible means to characterize the unfolding/refolding dynamics of individual …
Modulation of a protein-folding landscape revealed by AFM-based force spectroscopy notwithstanding instrumental limitations
DT Edwards, MA LeBlanc… - Proceedings of the …, 2021 - National Acad Sciences
Single-molecule force spectroscopy is a powerful tool for studying protein folding. Over the
last decade, a key question has emerged: how are changes in intrinsic biomolecular …
last decade, a key question has emerged: how are changes in intrinsic biomolecular …
Media advertising effects on consumer perception of orthodontic treatment quality
DT Edwards, B Shroff, SJ Lindauer… - The Angle …, 2008 - meridian.allenpress.com
Objective: To determine the effect of media advertising on consumer perception of
orthodontic treatment quality. Materials and Methods: A survey instrument was designed to …
orthodontic treatment quality. Materials and Methods: A survey instrument was designed to …