Rationale: It is commonly stated that mortality from acute respiratory distress syndrome
(ARDS) and acute lung injury (ALI) is decreasing. Objectives: To systematically review the …

© 2011 Canadian Medical Association or its licensors CMAJ, February 22, 2011, 183 (3)
E195 backgrounds in clinical and/or nonclinical expertise: 15 were experts in critical care …

The Charlson index is commonly used for risk adjustment in critical care health services
research. However, the literature supporting this methodology has not been thoroughly …

The efficacy of convalescent plasma for coronavirus disease 2019 (COVID-19) is unclear.
Although most randomized controlled trials have shown negative results, uncontrolled …

Context Severe acute kidney injury among hospitalized patients often necessitates initiation
of short-term dialysis. Little is known about the long-term outcome of those who survive to …

Rationale: Diaphragm dysfunction worsens outcomes in mechanically ventilated patients,
but the clinical impact of potentially preventable changes in diaphragm structure and …

Background Despite advances in defibrillation technology, shock-refractory ventricular
fibrillation remains common during out-of-hospital cardiac arrest. Double sequential external …

Background Few resources are available to support caregivers of patients who have
survived critical illness; consequently, the caregivers' own health may suffer. We studied …

Rationale: Disability risk groups and 1-year outcome after greater than or equal to 7 days of
mechanical ventilation (MV) in medical/surgical intensive care unit (ICU) patients are …

Background: Severe traumatic brain injury often leads to death from withdrawal of life-
sustaining therapy, although prognosis is difficult to determine. Methods: To evaluate …