User profiles for "author:Gavin Smith"
 | Gavin JD SmithProfessor, Duke-NUS Medical School, Singapore Verified email at duke-nus.edu.sg Cited by 24401 |
The emergence of pandemic influenza viruses
Pandemic influenza has posed an increasing threat to public health worldwide in the last
decade. In the 20th century, three human pandemic influenza outbreaks occurred in 1918 …
decade. In the 20th century, three human pandemic influenza outbreaks occurred in 1918 …
The ecology and adaptive evolution of influenza A interspecies transmission
U Joseph, YCF Su, D Vijaykrishna… - Influenza and other …, 2017 - Wiley Online Library
Since 2013, there have been several alarming influenza‐related events; the spread of highly
pathogenic avian influenza H5 viruses into North America, the detection of H10N8 and …
pathogenic avian influenza H5 viruses into North America, the detection of H10N8 and …
Avian influenza viruses in humans: lessons from past outbreaks
Background Human infections with avian influenza viruses (AIV) represent a persistent
public health threat. The principal risk factor governing human infection with AIV is from …
public health threat. The principal risk factor governing human infection with AIV is from …
[HTML][HTML] Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic
Abstract In March and early April 2009, a new swine-origin influenza A (H1N1) virus (S-OIV)
emerged in Mexico and the United States. During the first few weeks of surveillance, the …
emerged in Mexico and the United States. During the first few weeks of surveillance, the …
[HTML][HTML] Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia
MD De Jong, CP Simmons, TT Thanh, VM Hien… - Nature medicine, 2006 - nature.com
Abstract Avian influenza A (H5N1) viruses cause severe disease in humans,, but the basis
for their virulence remains unclear. In vitro and animal studies indicate that high and …
for their virulence remains unclear. In vitro and animal studies indicate that high and …
[HTML][HTML] Oseltamivir resistance during treatment of influenza A (H5N1) infection
MD De Jong, TT Thanh, TH Khanh… - New england journal …, 2005 - Mass Medical Soc
Influenza A (H5N1) virus with an amino acid substitution in neuraminidase conferring high-
level resistance to oseltamivir was isolated from two of eight Vietnamese patients during …
level resistance to oseltamivir was isolated from two of eight Vietnamese patients during …
[HTML][HTML] Effects of a major deletion in the SARS-CoV-2 genome on the severity of infection and the inflammatory response: an observational cohort study
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with a
382-nucleotide deletion (∆ 382) in the open reading frame 8 (ORF8) region of the genome …
382-nucleotide deletion (∆ 382) in the open reading frame 8 (ORF8) region of the genome …
Human infection with an avian H9N2 influenza A virus in Hong Kong in 2003
ABSTRACT Avian H9N2 influenza A virus has caused repeated human infections in Asia
since 1998. Here we report that an H9N2 influenza virus infected a 5-year-old child in Hong …
since 1998. Here we report that an H9N2 influenza virus infected a 5-year-old child in Hong …
[PDF][PDF] Early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients
Virus-specific humoral and cellular immunity act synergistically to protect the host from viral
infection. We interrogate the dynamic changes of virological and immunological parameters …
infection. We interrogate the dynamic changes of virological and immunological parameters …
Dating the emergence of pandemic influenza viruses
Pandemic influenza viruses cause significant mortality in humans. In the 20th century, 3
influenza viruses caused major pandemics: the 1918 H1N1 virus, the 1957 H2N2 virus, and …
influenza viruses caused major pandemics: the 1918 H1N1 virus, the 1957 H2N2 virus, and …