Stem cells generate the differentiated cell types within many organs throughout the lifespan
of an organism and are thus ultimately responsible for the longevity of multicellular …

Currently, the success of gene therapy is mainly limited due to the lack of effective vector
systems. Although viral vectors are highly efficient in transfecting cells, undesirable …

The design of artificial extracellular matrix (ECM) is important in tissue engineering because
artificial ECM regulates cellular behaviors, including proliferation, survival, migration, and …

Recent observations indicate that, in several types of human cancer, only a phenotypic
subset of cancer cells within each tumor is capable of initiating tumor growth. This functional …

UV light-emitting devices (LEDs) and laser diodes (LDs) are of interest for their potential use
in long-lifetime solidstate lighting, high-density information storage, secure communication …

Stem cells persist throughout life by self-renewing in numerous tissues including the central
and peripheral nervous systems. This raises the issue of whether there is a conserved …

Polycaprolactone (PCL) macromer was obtained by the reaction of PCL diol with acryloyl
chloride and confirmed using Fourier transform infrared and nuclear magnetic resonance …

Background Patients generally die of cancer after the failure of current therapies to eliminate
residual disease. A subpopulation of tumor cells, termed cancer stem cells (CSC), appears …

All cancers harbor molecular alterations in their genomes. The transcriptional consequences
of these somatic mutations have not yet been comprehensively explored in lung cancer …

The Wnt/β-catenin pathway, which signals through the Frizzled (Fzd) receptor family and
several coreceptors, has long been implicated in cancer. Here we demonstrate a therapeutic …