User profiles for "author:Isaac Thomsen"

Isaac Thomsen

Assistant Professor of Pediatrics, Vanderbilt University Medical Center
Verified email at vumc.org
Cited by 2503

Noninfectious manifestations and complications of chronic granulomatous disease

SE Henrickson, AM Jongco, KF Thomsen… - Journal of the …, 2018 - academic.oup.com
Chronic granulomatous disease (CGD), a primary immunodeficiency characterized by a
deficient neutrophil oxidative burst and the inadequate killing of microbes, is well known to …

A comprehensive approach to the management of children and adults with chronic granulomatous disease

IP Thomsen, MA Smith, SM Holland… - The Journal of Allergy and …, 2016 - Elsevier
Chronic granulomatous disease (CGD), a disease characterized by inadequate neutrophil
killing of microbial pathogens, affects 4 to 5 per million live births. For many decades …

[HTML][HTML] Epidemiological and Clinical Evidence for the Role of Toxins in S. aureus Human Disease

MR Bennett, IP Thomsen - Toxins, 2020 - mdpi.com
Staphylococcus aureus asymptomatically colonizes approximately 30–50% of the
population and is a leading cause of bacteremia, bone/joint infections, and skin infections in …

Effect of varying doses of a monovalent H7N9 influenza vaccine with and without AS03 and MF59 adjuvants on immune response: a randomized clinical trial

LA Jackson, JD Campbell, SE Frey, KM Edwards… - Jama, 2015 - jamanetwork.com
Importance Human infections with the avian influenza A (H7N9) virus were first reported in
China in 2013 and continue to occur. Hemagglutinin H7 administered alone is a poor …

Relationship Between Maternal and Neonatal Staphylococcus aureus Colonization

N Jimenez-Truque, S Tedeschi, EJ Saye… - …, 2012 - publications.aap.org
OBJECTIVE: The study aimed to assess whether maternal colonization with Staphylococcus
aureus during pregnancy or at delivery was associated with infant staphylococcal …

Novel risk factors for recurrent Clostridium difficile infection in children

MR Nicholson, IP Thomsen, JC Slaughter… - Journal of pediatric …, 2015 - journals.lww.com
Objectives: Clostridium difficile, a common cause of antibiotic-associated diarrhea, has been
reported to recur in high rates in adults. The rates and risk factors for recurrent C difficile …

Antibodies to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in All of Us Research Program Participants, 2 January to 18 March 2020

KN Althoff, DJ Schlueter, H Anton-Culver… - Clinical Infectious …, 2022 - academic.oup.com
Background With limited severe acute respiratory syndrome coronavirus (SARS-CoV-2)
testing capacity in the United States at the start of the epidemic (January–March 2020) …

Humoral and cellular immune responses to the SARS‐CoV‐2 BNT162b2 vaccine among a cohort of solid organ transplant recipients and healthy controls

A Yanis, Z Haddadin, AJ Spieker… - Transplant Infectious …, 2022 - Wiley Online Library
Background Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection is
associated with increased morbidity and mortality in solid organ transplant (SOT) recipients …

Children with invasive Staphylococcus aureus disease exhibit a potently neutralizing antibody response to the cytotoxin LukAB

IP Thomsen, AL DuMont, DBA James… - Infection and …, 2014 - Am Soc Microbiol
Despite the importance of Staphylococcus aureus as a common invasive bacterial
pathogen, the humoral response to infection remains inadequately defined, particularly in …

Clinical epidemiology and outcomes of pediatric musculoskeletal infections

J Yi, JB Wood, CB Creech, D Williams… - The Journal of …, 2021 - Elsevier
Objectives To understand the epidemiology of acute hematogenous osteomyelitis and septic
arthritis, including clinical and demographic features, microbiology, treatment approaches …