User profiles for "author:J Fraser"

James S. Fraser

- Verified email at ucsf.edu - Cited by 15112

James Fraser

- Verified email at uq.edu.au - Cited by 11043

Hyaluronan1

TC Laurent, JRE Fraser - The FASEB journal, 1992 - Wiley Online Library
Hyaluronan (hyaluronic acid) is a high‐molecular‐mass polysaccharide found in the
extracellular matrix, especially of soft connective tissues. It is synthesized in the plasma …

Hyaluronan: its nature, distribution, functions and turnover

JRE Fraser, TC Laurent… - Journal of internal …, 1997 - Wiley Online Library
Fraser JRE, Laurent TC, Laurent UBG (Monash University, Clayton, Victoria, Australia; and
University of Uppsala, Uppsala, Sweden). Hyaluronan: its nature, distribution, functions and …

Multipotential differentiation of adipose tissue-derived stem cells

BM Strem, KC Hicok, M Zhu, I Wulur… - The Keio journal of …, 2005 - jstage.jst.go.jp
Tissue engineering offers considerable promise in the repair or replacement of diseased
and/or damaged tissues. The cellular component of this regenerative approach will play a …

[HTML][HTML] A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier… - Nature, 2020 - nature.com
A newly described coronavirus named severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), which is the causative agent of coronavirus disease 2019 (COVID-19), has …

Human adipose tissue is a source of multipotent stem cells

PA Zuk, M Zhu, P Ashjian, DA De Ugarte… - Molecular biology of …, 2002 - Am Soc Cell Biol
Much of the work conducted on adult stem cells has focused on mesenchymal stem cells
(MSCs) found within the bone marrow stroma. Adipose tissue, like bone marrow, is derived …

Large language models generate functional protein sequences across diverse families

A Madani, B Krause, ER Greene, S Subramanian… - Nature …, 2023 - nature.com
Deep-learning language models have shown promise in various biotechnological
applications, including protein design and engineering. Here we describe ProGen, a …

Comparison of multi-lineage cells from human adipose tissue and bone marrow

…, B Thomas, P Benhaim, I Chen, J Fraser… - Cells tissues …, 2003 - karger.com
Our laboratory has recently characterized a population of cells from adipose tissue, termed
processed lipoaspirate (PLA) cells, which have multi-lineage potential similar to bone …

The Genome of the Basidiomycetous Yeast and Human Pathogen Cryptococcus neoformans

BJ Loftus, E Fung, P Roncaglia, D Rowley, P Amedeo… - Science, 2005 - science.org
Cryptococcus neoformans is a basidiomycetous yeast ubiquitous in the environment, a
model for fungal pathogenesis, and an opportunistic human pathogen of global importance …

Fat tissue: an underappreciated source of stem cells for biotechnology

JK Fraser, I Wulur, Z Alfonso, MH Hedrick - Trends in biotechnology, 2006 - cell.com
Adipose tissue can be harvested in large amounts with minimal morbidity. It contains
numerous cells types, including adipocytes, preadipocytes, vascular endothelial cells and …

Extracorporeal membrane oxygenation support in COVID-19: an international cohort study of the Extracorporeal Life Support Organization registry

…, N Barrett, J Bělohlávek, D Fisher, J Fraser… - The Lancet, 2020 - thelancet.com
Background Multiple major health organisations recommend the use of extracorporeal
membrane oxygenation (ECMO) support for COVID-19-related acute hypoxaemic …