[HTML][HTML] The zebrafish reference genome sequence and its relationship to the human genome
Zebrafish have become a popular organism for the study of vertebrate gene function,. The
virtually transparent embryos of this species, and the ability to accelerate genetic studies by …
virtually transparent embryos of this species, and the ability to accelerate genetic studies by …
[HTML][HTML] Towards complete and error-free genome assemblies of all vertebrate species
High-quality and complete reference genome assemblies are fundamental for the
application of genomics to biology, disease, and biodiversity conservation. However, such …
application of genomics to biology, disease, and biodiversity conservation. However, such …
Significantly improving the quality of genome assemblies through curation
K Howe, W Chow, J Collins, S Pelan, DL Pointon… - …, 2021 - academic.oup.com
Genome sequence assemblies provide the basis for our understanding of biology.
Generating error-free assemblies is therefore the ultimate, but sadly still unachieved goal of …
Generating error-free assemblies is therefore the ultimate, but sadly still unachieved goal of …
Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly
VA Schneider, T Graves-Lindsay, K Howe… - Genome …, 2017 - genome.cshlp.org
The human reference genome assembly plays a central role in nearly all aspects of today's
basic and clinical research. GRCh38 is the first coordinate-changing assembly update since …
basic and clinical research. GRCh38 is the first coordinate-changing assembly update since …
[HTML][HTML] Modernizing reference genome assemblies
DM Church, VA Schneider, T Graves, K Auger… - PLoS …, 2011 - journals.plos.org
The availability of a high quality human genome assembly has revolutionized biomedical
research. Genomics has now entered the realm of clinical genetics, with many groups using …
research. Genomics has now entered the realm of clinical genetics, with many groups using …
[HTML][HTML] Semi-automated assembly of high-quality diploid human reference genomes
The current human reference genome, GRCh38, represents over 20 years of effort to
generate a high-quality assembly, which has benefitted society,. However, it still has many …
generate a high-quality assembly, which has benefitted society,. However, it still has many …
[HTML][HTML] Sixteen diverse laboratory mouse reference genomes define strain-specific haplotypes and novel functional loci
We report full-length draft de novo genome assemblies for 16 widely used inbred mouse
strains and find extensive strain-specific haplotype variation. We identify and characterize …
strains and find extensive strain-specific haplotype variation. We identify and characterize …
Scalable, accessible and reproducible reference genome assembly and evaluation in Galaxy
D Larivière, L Abueg, N Brajuka, C Gallardo-Alba… - Nature …, 2024 - nature.com
The Earth BioGenome Project aims to produce reference genomes for all~ 1.8 million known
eukaryotic species over the next decade 1–4. Achieving this goal will require the current …
eukaryotic species over the next decade 1–4. Achieving this goal will require the current …
[PDF][PDF] A chromosome-level reference genome and pangenome for barn swallow population genomics
S Secomandi, GR Gallo, M Sozzoni, A Iannucci… - Cell reports, 2023 - cell.com
Insights into the evolution of non-model organisms are limited by the lack of reference
genomes of high accuracy, completeness, and contiguity. Here, we present a chromosome …
genomes of high accuracy, completeness, and contiguity. Here, we present a chromosome …
[HTML][HTML] The admixed brushtail possum genome reveals invasion history in New Zealand and novel imprinted genes
Combining genome assembly with population and functional genomics can provide
valuable insights to development and evolution, as well as tools for species management …
valuable insights to development and evolution, as well as tools for species management …