Infection strategies of enteric pathogenic Escherichia coli

A Clements, JC Young, N Constantinou, G Frankel - Gut microbes, 2012 - Taylor & Francis
Enteric Escherichia coli (E. coli) are both natural flora of humans and important pathogens
causing significant morbidity and mortality worldwide. Traditionally enteric E. coli have been …

Rapid rule-out of acute myocardial infarction with a single high-sensitivity cardiac troponin T measurement below the limit of detection: a collaborative meta-analysis

JW Pickering, MP Than, L Cullen, S Aldous… - Annals of internal …, 2017 - acpjournals.org
This article has been corrected. The original version (PDF) is appended to this article as a
Supplement. Background: High-sensitivity assays for cardiac troponin T (hs-cTnT) are …

Inflammatory biomarkers for predicting cardiovascular disease

L Stoner, AA Lucero, BR Palmer, LM Jones… - Clinical …, 2013 - Elsevier
The pathology of cardiovascular disease (CVD) is complex; multiple biological pathways
have been implicated, including, but not limited to, inflammation and oxidative stress …

Long-term effects of child abuse and neglect on emotion processing in adulthood

JC Young, CS Widom - Child abuse & neglect, 2014 - Elsevier
To determine whether child maltreatment has a long-term impact on emotion processing
abilities in adulthood and whether IQ, psychopathology, or psychopathy mediate the …

[HTML][HTML] Betaine and Trimethylamine-N-Oxide as Predictors of Cardiovascular Outcomes Show Different Patterns in Diabetes Mellitus: An Observational Study

M Lever, PM George, S Slow, D Bellamy, JM Young… - PloS one, 2014 - journals.plos.org
Background Betaine is a major osmolyte, also important in methyl group metabolism.
Concentrations of betaine, its metabolite dimethylglycine and analog trimethylamine-N …

Effect of coenzyme Q10 supplementation on simvastatin-induced myalgia

JM Young, CM Florkowski, SL Molyneux… - The American journal of …, 2007 - Elsevier
Myalgia is the most frequently reported adverse side effect associated with statin therapy
and often necessitates reduction in dose, or the cessation of therapy, compromising …

[HTML][HTML] Assessments of arterial stiffness and endothelial function using pulse wave analysis

L Stoner, JM Young, S Fryer - International journal of vascular …, 2012 - hindawi.com
Conventionally, the assessments of endothelial function and arterial stiffness require
different sets of equipment, making the inclusion of both tests impractical for clinical and …

A 2-hour diagnostic protocol for possible cardiac chest pain in the emergency department: a randomized clinical trial

M Than, S Aldous, SJ Lord, S Goodacre… - JAMA internal …, 2014 - jamanetwork.com
Importance Patients with chest pain represent a high health care burden, but it may be
possible to identify a patient group with a low short-term risk of adverse cardiac events who …

[HTML][HTML] Coenzyme Q10: is there a clinical role and a case for measurement?

SL Molyneux, JM Young, CM Florkowski… - The Clinical …, 2008 - ncbi.nlm.nih.gov
Abstract Coenzyme Q 10 (CoQ 10) is an essential cofactor in the mitochondrial electron
transport pathway, and is also a lipid-soluble antioxidant. It is endogenously synthesised via …

[HTML][HTML] Effectiveness of EDACS versus ADAPT accelerated diagnostic pathways for chest pain: a pragmatic randomized controlled trial embedded within practice

MP Than, JW Pickering, SJ Aldous, L Cullen… - Annals of emergency …, 2016 - Elsevier
Study objective A 2-hour accelerated diagnostic pathway based on the Thrombolysis in
Myocardial Infarction score, ECG, and troponin measures (ADAPT-ADP) increased early …